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Transplant of fresh brain cells replaces diseased and aged ones

Researchers have transplanted cells capable of forming specialized brain support cells into mice brains and found that they not only competed with and replaced unhealthy cells but aged ones, too. The findings open the door to developing an effective treatment for a range of conditions like multiple sclerosis, ALS, Alzheimer’s disease, autism and schizophrenia.

‘Glial cells’ is an umbrella term for the cells that are a support system to nerve cells (neurons). Progenitor cells are descendants of stem cells that can differentiate into specific cell types, and, in the case of glial cells, human glial progenitor cells (hGPCs) differentiate into subtypes, including astrocytes and oligodendrocytes, specialized for particular functions.

Astrocytes comprise most of our central nervous system cells, providing support and protection for neurons, transporting nutrients and removing waste. Oligodendrocytes lay down and maintain the lipid-rich, insulating wrapping called myelin around some axons, the part of the neuron that connects with another neuron and allows the transmission of nerve impulses.

Distinguished Lecture Series | Why life began with RNA | Trivedi School of Biosciences

This video, which is a part of the Distinguished Lecture Series by Trivedi School of Biosciences, Ashoka University, Prof. Jack W. Szostak discusses why life began with RNA. Why was Ribose sugar chosen in the primordial soup, and not several other alternative sugars that may have been available? He shows this using elegant experiments that include chemistry and structural biology.

Distinguished Speaker: Prof. Jack W. Szostak.
2009 Nobel Laureate in Physiology or Medicine.

#structuralbiologylecture #nobellaureate #medicine

The Origin of Life: Not as Hard as it Looks? Jack Szosta, Spring 2023 Eyring Lecturer

Nobel laureate Jack Szostak from University of Chicago delivered the Eyring General Lecture on March 17, 2023 at Arizona State University. Please click here to learn more about Dr. Szosta and the distinguished Eyring Lecture Series at ASU. https://news.asu.edu/20230309-nobel-laureate-jack-szostak-de…series-asu.

#chemistry #research @arizonastateuniversity @ASUNews