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Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

Recently identified by the Food and Drug Administration as a public health crisis, osteoarthritis affects more than 520 million people worldwide who deal with pain and . Osteoarthritis is typically induced by mechanical or traumatic stress in the joint, leading to damaged that cannot be repaired naturally.

“Without better understanding of what drives the initiation and progression of osteoarthritis, effective treatment has been limited,” said lead author Johanna Bolander of WFIRM. “Initially, we studied what goes wrong in osteoarthritic joints, compared these processes to functional environments, and used this information to develop an immunotherapy cell treatment.”

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The field of plate tectonics is relatively new, and researchers are still uncovering the intricacies of geologic faults that cause earthquakes. One such fault, the Cascadia Subduction Zone, is a potentially catastrophic offshore fault located in the Pacific Northwest that has yet to reveal all its secrets. Despite its eerie calmness, it is capable of producing a massive magnitude-9 quake.

A study led by the University of Washington discovered seeps of warm, chemically distinct liquid shooting up from the seafloor about 50 miles off Newport, Oregon. Their research, published in the journal Science Advances.

<em>Science Advances</em> is a peer-reviewed, open-access scientific journal that is published by the American Association for the Advancement of Science (AAAS). It was launched in 2015 and covers a wide range of topics in the natural sciences, including biology, chemistry, earth and environmental sciences, materials science, and physics.

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Scientists have analyzed the brightest gamma-ray burst (GRB) ever detected, named the BOAT (Brightest Of All Time) and GRB 221009A, which was observed by NASA

Established in 1958, the National Aeronautics and Space Administration (NASA) is an independent agency of the United States Federal Government that succeeded the National Advisory Committee for Aeronautics (NACA). It is responsible for the civilian space program, as well as aeronautics and aerospace research. Its vision is “To discover and expand knowledge for the benefit of humanity.” Its core values are “safety, integrity, teamwork, excellence, and inclusion.” NASA conducts research, develops technology and launches missions to explore and study Earth, the solar system, and the universe beyond. It also works to advance the state of knowledge in a wide range of scientific fields, including Earth and space science, planetary science, astrophysics, and heliophysics, and it collaborates with private companies and international partners to achieve its goals.

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Researchers at The University of Manchester have discovered record-high magnetoresistance in graphene.

Graphene is an allotrope of carbon in the form of a single layer of atoms in a two-dimensional hexagonal lattice in which one atom forms each vertex. It is the basic structural element of other allotropes of carbon, including graphite, charcoal, carbon nanotubes, and fullerenes. In proportion to its thickness, it is about 100 times stronger than the strongest steel.

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Some people might be regretting throwing their old cassette tapes.

In the music world, vinyl records get a lot of attention when it comes to physical media. Sales for vinyl records have been on the rise for years, and now the same thing is starting to happen with cassette tapes.

The resurgence of vinyl records has been so strong that it’s not really even a “trend” anymore. In 2021, people spent more on vinyl than CDs for the first time since 1986. Cassette tape sales, on the other hand, have been very low for a long time. However, in the last five years, things are changing.

The cassette tape was introduced in 1963 by Philips. The first cassettes could hold 45 minutes of music on each side, which was much more than vinyl records. But perhaps the biggest advantage of cassette tapes was their compact size.

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