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#universe #weirdworld #science.

From the smallest atom to the largest galaxy, everything in the universe obeys the laws of physics, where our brains are made of the same atoms and molecules as the rest of the universe. So could we take this theory further and ask whether consciousness could be part of the underlying fabric of the universe. Humans have also managed to extend this to the internet where there is an eerie pattern between the universe the brain and the internet where experts have been asking the question whether the internet could one day develop its own consciousness. Maybe in the distant future all three will unite into one giant mind. Humans have always been fascinated with the thought that the universe somehow reflects us and whether the universe could be a giant brain. Let’s delve deeper into the trinity that is the universe, the brain and the internet.

Credits:
https://www.cbsnews.com/news/universe-grows-like-a-giant-brain/

Your Brain, the Internet and the Universe Have Something Fascinating in Common

Music From AudioBlocks.com, Pond5.com.

Continue reading “3 Signs The UNIVERSE IS ACTUALLY A GIANT BRAIN” | >

Researchers hope KRAS test can serve renewed function as soon as possible Scientists have found an existing gene test frequently used on the NHS can also shed light on whether a bowel cancer patient will respond positively or negatively to chemotherapy. Researchers from The Institute of Cancer Research, Imperial College London and the Netherlands Cancer Institute have found the KRAS test can have use beyond its current function of predicting how patients will react to cancer drug cetuximab.

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While the mental has often played second fiddle to the physical when it comes to longevity research, this is changing – and not a moment too soon.

The physical and mental aspects of aging are interconnected, and given the strong connection between psychology and the physical pace of aging, poor mental health is starting to be recognised as a major driver of aging.

A raft of developments have demonstrated that physical lifespan and healthspan can be extended and improved, and now it is time for the longevity industry to achieve similar success when it comes to mental health. Sergey Jakimov, the CEO of Swiss investment group LongeVC agrees, and tells us why it’s time for VCs to get excited about backing startups delivering cutting-edge solutions for mental healthcare.

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As a survival mechanism, some tumors, particularly many solid tumors, have evolved to express the ligands capable of turning off the immune response. While immune regulation benefits us under normal conditions, any hindrance of the immune response in the presence of cancer can become detrimental. Understanding these biological processes has led to the development of a promising immunotherapeutic modality: the immune checkpoint inhibitor (ICI). ICIs work by blocking the signals that dampen the immune response.

One prominent checkpoint pathway consists of programmed death 1 (PD1), located on immune cells, and programmed death ligand 1 (PD-L1), expressed on tumor cells. The FDA has approved numerous ICIs to block the interaction of PD-1 and PD-L1 for patients with various solid tumors, including skin, lung, and liver cancers.

Predicting the patients most likely to benefit from PD-1/PD-L1 interventions remains a high priority. Depending on the type of cancer, different tests can predict a patient’s likelihood of responding to ICIs. In some cancers, a readout used to access ICI responsiveness is a patient’s tumor mutational burden (TMB), an estimate of how many mutations appear in the cancer genome. However, better predictive models could help identify more patients who could benefit from these therapies.

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At just 40 years old, Kristen Fortney has spent more than half of her life thinking about the science of aging. But why?

“When I get asked this question I usually blame it on reading too much science fiction,” the CEO and co-founder of the clinical-stage biotech BioAge Labs said with a laugh. “My co-founder, Eric Morgen, and I have been talking about aging since high school.”

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George Church is a geneticist known for his pioneering work in developing new technologies for genome sequencing, editing, and synthesis. He has also been involved in research on genome engineering and gene therapy.

Links.

George Church, Ph.D.


https://arep.med.harvard.edu/

PODCAST INFO:
The Learning With Lowell show is a series for the everyday mammal. In this show we’ll learn about leadership, science, and people building their change into the world. The goal is to dig deeply into people who most of us wouldn’t normally ever get to hear. The Host of the show – Lowell Thompson-is a lifelong autodidact, serial problem solver, and founder of startups.

LINKS
Youtube: https://www.youtube.com/channel/UCzri06unR-lMXbl6sqWP_-Q
Youtube clips: https://www.youtube.com/channel/UC-B5x371AzTGgK-_q3U_KfA
Linkedin: https://www.linkedin.com/in/lowell-thompson-2227b074
Twitter: https://twitter.com/LWThompson5
Website: https://www.learningwithlowell.com/

Timestamp / show notes.
00:00 Intro.
00:40 Changing millions of lives.
01:35 Unknowns in Biology / Fan question.
04:30 Space / Aliens.
05:18 Exciting projects.
08:15 Sequencing 8 billion people.
10:25 Making Organisms Virus proof.
12:00 Viruses adapting to changing.
15:55 Making IP actionable.
18:25 Transition to startups / issues.
22:30 Longevity and healthspan for older populations.
27:20 Rejuvenation vs cure.
29:40 Last 5 years/ surprises.
33:10 1 million cell edits.
34:40 Reduced returns with more edits at one time.
38:20 Software as biology / opportunity in biotech.
41:35 Hiding data in cells.
43:40 Synthetic biology relieving poverty.
47:45 Biohacking, chinese box, relieving poverty continues.
50:53 Producing good/submarine.
53:25 Synthetic biology for energy production.
57:51 Wooly mammoth genes / fan q.
1:02:30 Control characteristics with food.
1:03:50 Expediting gestation period.
1:06:00 External womb.
1:08:55 Problems /tools he wishes he had.
1:12:25 Cost of gene therapies from rejuvenation bio / fan question.
1:18:22 Virus gene drive.
1:21:10 Next 10 years.
1:23:02 CIRSPR CRPS pain question.
1:26:33 Books.
1:32:42 Calico lab CTO?

#georgechurch #syntheticbiology #biomanufacturing

Continue reading “George Church: Biomanufacturing, CRISPR,1 million cell edits, Woolly mammoth-Learning with Lowell-164” | >