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Clinical trial shows taking blood pressure medication at night improves nocturnal and daytime control

Research led by Sichuan University in China has revealed that bedtime antihypertensive medication dosing improves nocturnal blood pressure control over morning dosing in patients with hypertension.

Hypertension is a major global health challenge. In China, nearly 300 million individuals live with elevated blood pressure and fewer than 17% achieve adequate control. Nocturnal pressure is often the most difficult to manage and can be a better predictor of heart attack and stroke than daytime readings.

Previous studies have examined the optimal timing for antihypertensive medication with conflicting evidence and substantial variability in study outcomes.

New gene tool leads to better treatments for complex diseases

Genetic changes can signal evidence of disease, but pinpointing which genes and what’s changed can be difficult.

But in a study of traits that offer clues to a person’s —such as lipid and and inflammation—a team of researchers at Case Western Reserve University devised a and tool to improve how genes and genetic changes that cause diseases are identified.

Their new approach could allow doctors to detect and treat so-called cardiometabolic diseases earlier in their development. Their findings were recently published in the journal Nature Communications.

Precipitation extremes in 2024 Reviews Earth & Environment

2024 was one of the wettest years on record, witnessing record-breaking extreme precipitation events across the globe, several of which were compound events. Extreme rainfalls were unprecedented in arid regions and parts of the Global South, with severe monsoon rains and rapidly intensifying tropical cyclones causing severe casualties and economic losses.

Vertex Presents Positive Data for Zimislecel in Type 1 Diabetes at the American Diabetes Association 85th Scientific Sessions

– Results from the study continue to demonstrate the transformative potential of zimislecel with consistent and durable patient benefit – – All 12 patients with at least one year of follow-up who received a full dose of zimislecel as a single infusion achieved ADA –recommended target HbA1c levels…

NASA’s Parker Probe Just Dived Into the Sun’s Atmosphere and Solved a Fiery Solar Mystery

The ‘helicity barrier’ has been directly confirmed, offering new insights into the heating and formation of the solar wind. Scientists have long been puzzled by an unusual solar mystery: the Sun’s outer atmosphere, called the corona, is vastly hotter than the surface below it. Adding to the intrigu