In a first, physicists have directly seen Hofstadter’s butterfly—a long-sought-after fractal in the quantum realm
Allogeneic cell therapeutics are currently being developed to overcome manufacturing bottlenecks of autologous products but face allorejection as their biggest obstacle. This review analyzes the immunogenicity of allogeneic cell therapeutics, outlines engineering strategies for immune evasion, and summarizes recent milestone achievements.
Researchers categorized participants by whether or not they had experienced SCD, and by their antidepressant medication use — between 1 and 5 years, or 6 years and longer.
At the study’s conclusion, researchers found that participants who used antidepressants for a period of 1 to 5 years had a 56% increased risk of SCD.
Participants who used antidepressants for 6 or more years had a 2.2 times higher risk for SCD.
A new study from Cedars-Sinai has examined whether a specialized diet could improve symptoms of gastrointestinal disorders linked to an imbalance in gut microbiota.
The research tested the elemental diet’s effectiveness and explored whether improving its unappealing taste—a major barrier—could help patients adhere to the diet’s stringent protocol. The investigators’ findings were published in the peer-reviewed journal Clinical Gastroenterology and Hepatology.
The elemental diet is a special low-fat liquid formulation that is designed to be easily digested and contains all the essential nutrients necessary for a healthy diet. A few prior studies have shown that the diet has the potential to improve challenging symptoms associated with digestive issues like small intestinal bacterial overgrowth (SIBO), intestinal methanogen overgrowth (IMO), Crohn’s disease, eosinophilic esophagitis and other gut ailments.
By doing more and more of our “thinking” for us, artificial intelligence may be diminishing our critical thinking skills.
There is an urgent need for precision immunotherapy strategies that simultaneously target both tumor cells and immune cells to enhance treatment efficacy. Identifying genes with dual functions in both cancer and immune cells opens new possibilities for overcoming tumor resistance and improving patient survival.
Professor Zeng Zexian’s team from the Center for Quantitative Biology at the Peking University Academy for Advanced Interdisciplinary Studies, in collaboration with the Peking University-Tsinghua University Joint Center for Life Sciences, has developed ICRAFT, an innovative computational platform for identifying cancer immunotherapy targets. Their study has been published in Immunity.
ICRAFT integrates 558 CRISPR screening datasets, 2 million single-cell RNA sequencing datasets, and 943 RNA-Seq datasets from clinical immunotherapy samples.
Present a preclinical study on mice and macaques demonstrating the safety and efficacy of YCT-529, a drug forming the basis of the “first non-hormonal male birth control pill”. This research is from a startup called YourChoice Therapeutics — which is now working on human clinical trials. Exciting to see reproductive medicine advancing in this direction! #reproductivehealth.
[ https://www.nature.com/articles/s43856-025-00752-7](https://www.nature.com/articles/s43856-025-00752-7)
Euclid is on a quest to unravel one of the universe’s greatest mysteries: why it’s expanding faster and faster. With help from NASA, this space telescope is capturing sweeping views of billions of galaxies, allowing scientists to peer into the deep past. Using light that took billions of years to
Q.ANT announces production of its revolutionary light-powered AI chip, promising 50x faster speeds and 30x better energy efficiency.
A breakthrough Cu-Ta-Li alloy has the potential to revolutionize aerospace, defense, and industrial applications. Researchers from the U.S. Army Research Laboratory (ARL) and Lehigh University have developed an advanced nanostructured copper alloy that sets a new benchmark for high-temperature perf