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Whether it’s our phones, cars, televisions, medical devices or even washing machines, we now have computers everywhere.

Using bigger computers, we solve bigger problems like managing the operation of a power grid, designing an aircraft, predicting the weather or providing different types of artificial intelligence (AI).

But all these machines work by manipulating data in the form of ones and zeros (bits) using classical techniques that have not changed since the abacus was invented in antiquity.

In case you thought science was going to take a day off, researchers have just figured out a way of reversing brain aging – in fruit flies, but still.

They previously did something similar in lab mice, claiming to “reverse and repair” damage done by Alzheimer’s disease. The brain is a fascinating thing: it behaves weirdly after midnight, performs a magical reset while sleeping to “save memories,” and automatically corrects spelling errors even when you don’t see them yourself. Whatever next, health experts?!

When a common type of protein builds up in the brain, it stops cells from getting rid of “unnecessary or dysfunctional components,” i.e., waste.

It was a moment three years in the making, based on intensive research and design work: On Sept. 5, for the first time, a large high-temperature superconducting electromagnet was ramped up to a field strength of 20 tesla, the most powerful magnetic field of its kind ever created on Earth.


The next step will be building SPARC, a smaller-scale version of the planned ARC power plant. The successful operation of SPARC will demonstrate that a full-scale commercial fusion power plant is practical, clearing the way for rapid design and construction of that pioneering device can then proceed full speed.

Zuber says that “I now am genuinely optimistic that SPARC can achieve net positive energy, based on the demonstrated performance of the magnets. The next step is to scale up, to build an actual power plant. There are still many challenges ahead, not the least of which is developing a design that allows for reliable, sustained operation. And realizing that the goal here is commercialization, another major challenge will be economic. How do you design these power plants so it will be cost effective to build and deploy them?”

Someday in a hoped-for future, when there may be thousands of fusion plants powering clean electric grids around the world, Zuber says, “I think we’re going to look back and think about how we got there, and I think the demonstration of the magnet technology, for me, is the time when I believed that, wow, we can really do this.”

Data is power. According to Dinesh Bharadia, an associate professor at UC San Diego in the Department of Electrical and Computer Engineering with an affiliate appointment in the Department of Computer Science and Engineering and the Qualcomm Institute (QI), “data will be the next decade’s ‘silicon.’”

The rapid growth of the Internet of Things means that data is more readily available and easily accessible than ever. Sensors, “smart” devices and software connect our world to the cloud, gathering information and enabling new types of data sharing and analysis. However, most of these tools are battery-powered and have difficulty sensing changes in real time.

Now, the tide is turning.

Recent research reveals that the immune system interacts with the body’s internal clock, influencing both fat storage and temperature regulation.

The discovery hints at why shift workers and others with irregular work, eating, or sleep patterns driven by the demands of modern life fall out of metabolic sync, and may hold potential for developing therapies to address obesity and prevent wasting.

The key finding—that an immune molecule within adipose (fat) tissue, known as interleukin-17A (IL-17A), plays a regulatory role in fat storage—holds significant therapeutic potential for addressing obesity, preventing wasting, and mitigating other metabolic disorders. By targeting this molecule, drug developers may gain a valuable new pathway for creating treatments aimed at these conditions.

KAIST researchers have developed a groundbreaking single-atom editing technology using light-powered “molecular scissors” to convert oxygen atoms into nitrogen in drug compounds, simplifying drug development and boosting efficacy.

In the field of pioneering drug development, a groundbreaking new technology that enables the precise and rapid editing of key atoms critical to drug efficacy has been hailed as a transformative and “dream” innovation, revolutionizing the process of discovering potential drug candidates. Researchers at KAIST have achieved a world-first by successfully developing single-atom editing technology designed to maximize drug efficacy.

On October 8th, KAIST (represented by President Kwang-Hyung Lee) announced that Professor Yoonsu Park’s research team from the Department of Chemistry successfully developed technology that enables the easy editing and correction of oxygen atoms in furan compounds into nitrogen atoms, directly converting them into pyrrole frameworks, which are widely used in pharmaceuticals.

Gamma radiation converts methane into glycine and other complex molecules. Gamma radiation can convert methane into a wide variety of products at room temperature, including hydrocarbons, oxygen-containing molecules, and amino acids, reports a research team in the journal Angewandte Chemie. This type of reaction probably plays an important role in the formation of complex organic molecules in the universe — and possibly in the origin of life. They also open up new strategies for the industrial conversion of methane into high value-added products under mild conditions.

With these research results, the team led by Weixin Huang at the University of Science and Technology of China (Hefei) has contributed to our fundamental understanding of the early development of molecules in the universe.

“Gamma rays, high-energy photons commonly existing in cosmic rays and unstable isotope decay, provide external energy to drive chemical reactions of simple molecules in the icy mantles of interstellar dust and ice grains,” states Huang.

For every yellow star like our own there are ten times as many smaller stars. Red Dwarfs are the most common type of star, outnumbering all the others combined, and as we head out into interstellar space to colonize the galaxy, the exoplanets around these red alien suns may be the most common home for settlers.

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Credits:
Colonizing Red Dwarfs.
Science \& Futurism with Isaac Arthur.
Episode 275, January 27, 2021
Written, Produced \& Narrated by Isaac Arthur.

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My name is Artem, I’m a graduate student at NYU Center for Neural Science and researcher at Flatiron Institute (Center for Computational Neuroscience).

In this video, we explore the Nobel Prize-winning Hodgkin-Huxley model, the foundational equation of computational neuroscience that reveals how neurons generate electrical signals. We break down the biophysical principles of neural computation, from membrane voltage to ion channels, showing how mathematical equations capture the elegant dance of charged particles that enables information processing.