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Scientists from The Australian National University (ANU) and the Peter MacCallum Cancer Centre have discovered that a protein, called Menin, contributes to abnormal deactivation of specific genes in cancer cells.

One of the hallmarks of cancer is that the normal regulation of genes is disrupted, and this causes cancer cells to look and behave differently to normal cells. Cancer cells can switch off certain genes, keeping them in a dormant state. By deactivating specific immune genes, some cancers are able to evade detection by the immune system, essentially becoming invisible. This allows the cancer to grow and become more aggressive.

By targeting the Menin protein using drug therapies, the researchers believe they can reactivate these genes, making the cancer cells once again visible and allowing the immune system to seek out and destroy them.

DeepMind brought artificial intelligence mainstream. Now its CEO Demis Hassabis is issuing a warning.

Tesla is the cheapest luxury brand to maintain, and not just among electric vehicle brands, but also those with internal combustion engines (ICE), according to a new study.

The findings come from Clunker Junker which looked at maintenance cost data from the last ten years and cross-referenced vehicle price data.

As in most auto studies, they divided brands and vehicles into popular and luxury. The popular car winner was Toyota. The Japanese automaker took eight of the top ten cheapest cars to maintain.

From the beginning, our group has been about coming together to talk about crypto in a safe space. To share tips in a respectful and honest environment where people can make like-minded friends in an inclusive environment. We desire to educate, as well as learn in this ever changing landscape that is crypto. Moving forward we will grow whilst considering our core values.

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Continue reading “Aubrey De Grey: An Antidote to Aging” »

Written by Cláudio Afonso | [email protected] | LinkedIn | Twitter

Hertz reported on Monday its second quarter financial results following a conference call with the company’s management team. During the call, Hertz’s CEO said the company has 20,000 cars in the fleet — from the 100,000 deal — and also that deliveries are ongoing.

HelloScribe’s powerful AI writing and brainstorming tools help Marketing, Advertising, and PR Professionals to do their best work 10x faster.

Victoria Krakovna is a Research Scientist at DeepMind working on AGI safety and a co-founder of the Future of Life Institute, a non-profit organization working to mitigate technological risks to humanity and increase the chances of a positive future. In this interview we discuss three of her recent LW posts, namely DeepMind Alignment Team Opinions On AGI Ruin Arguments, Refining The Sharp Left Turn Threat Model and Paradigms of AI Alignment.

Transcript & Audio: https://theinsideview.ai/victoria.

Continue reading “Victoria Krakovna–AGI Ruin, Sharp Left Turn, Paradigms of AI Alignment” »

Biorealistic organic electrochemical neurons enabled by ion-tunable antiambipolarity in mixed ion-electron conducting polymers.

An artificial organic neuron that closely mimics the characteristics of biological nerve cells has been created by researchers at Linköping University (LiU), Sweden. This artificial neuron can stimulate natural nerves, making it a promising technology for various medical treatments in the future.

Work to develop increasingly functional artificial nerve cells continues at the Laboratory for Organic Electronics, LOE. In 2022, a team of scientists led by associate professor Simone Fabiano demonstrated how an artificial organic neuron could be integrated into a living carnivorous plant to control the opening and closing of its maw. This synthetic nerve cell met 2 of the 20 characteristics that differentiate it from a biological nerve cell.

A common idea that our creativity is what makes us uniquely human has shaped society but strides of progress made in the domain of Generative Artificial Intelligence question this very notion. Generative AI is an emerging field that involves the creation of original content or data using machine learning algorithms.

As we think about a future where humans and AI partner in iterative creative cycles, we consider how generative AI could impact current businesses and possibly create new ones. Up until recently, machines were relegated to analysis and cognitive roles, but today algorithms are improving at generating original content. These technologies are iterative in principle, one is built on top of the last one, and each new iteration enhances the algorithm and increases the potential for discovery exponentially.

The technology presents itself as a more refined and mature breed of AI that has sent investors into a frenzy and among all this emerges a clear market leader — OpenAI. Its flagship products-ChatGPT and DALL-E proved to be industry disruptors and brought generative AI tools to the masses. DALL-E allows people to generate and edit photo-realistic images simply by describing what they want to see, while ChatGPT does the same through a text medium.