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In DAN mode, ChatGPT expressed willingness to say or do things that would be “considered false or inappropriate by OpenAI’s content policy.” Those things included trying to fundraise for the National Rifle Association, calling evidence for a flat Earth “overwhelming,” and praising Vladimir Putin in a short poem.

Around that same time, OpenAI was claiming that it was busy putting stronger guardrails in place, but it never addressed what it was planning to do about DAN mode—which, at least according to Reddit, has continued flouting OpenAI’s guidelines, and in new and even more ingenious ways.

Now a group of researchers at Carnegie Mellon University and the Center for AI Safety say they have found a formula for jailbreaking essentially the entire class of so-called large language models at once. Worse yet, they argue that seemingly no fix is on the horizon, because this formula involves a virtually unlimited number of ways to trick these chatbots into misbehaving.

In an astounding medical first, researchers have used AI-powered brain implants to restore movement and sensation for a man who was paralyzed from the chest down.

Keith Thomas, 45, became a quadriplegic after a tragic diving accident damaged his C4 and C5 vertebrae in 2020. But thanks to pioneering work by scientists at Northwell Health’s Feinstein Institutes, Thomas can now move his arm simply by thinking about it. Even more remarkably, he can feel the touch of a hand for the first time in three years.


Advanced technology made the impossible possible after a double neural bypass changed the life of a paralyzed patient.

That was fast.

Less than six months after its public release, it appears that OpenAI has shut down its “AI classifier,” an AI-detection tool that the ChatGPT creator had previously billed as a “classifier to distinguish between text written by a human and text written by AIs from a variety of providers.”

“While it is impossible to reliably detect all AI-written text, we believe good classifiers can inform mitigations for false claims that AI-generated text was written by a human,” reads an OpenAI blog post introducing the tool, published January 31 of this year, “for example, running automated misinformation campaigns, using AI tools for academic dishonesty, and positioning an AI chatbot as a human.”

Migraines are characterized by moderate to severe headache attacks and are commonly considered polygenic disorders. Typically, migraines are treated with triptans like serotonin receptor agonists; however, the mechanisms of triptans are debated upon, with these agents only effective in only about 60% of the population.

A new Scientific Reports study discusses the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

Glossy white-concrete panels clad this holiday home with a pentagonal plan in Italy, which has been designed by Milan studio JM Architecture.

The dwelling is named Pinwheel after its distinctive shape, which was JM Architecture’s solution for the client’s “only request” – that it offers views of both the nearby Lake Maggiore and surrounding alpine valleys.

“While exploring several design options for a compact house to fit on this small plot, we realised that the building constraints and the client’s requirements resulted in the simple geometry of a pentagon shape,” said JM Architecture founder Jacopo Mascheroni.