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Astronomers from the University of Maryland and the Michigan Technological University, have inspected a mysterious ultra-high energy gamma-ray source known as LHAASO J2108+5157. Results of the study, published August 31 on the pre-print server arXiv, could help us unveil the true nature of this source.

Sources emitting with photon energies between 100 GeV and 100 TeV are called very-high energy (VHE) gamma-ray sources, while those with above 0.1 PeV are known as ultra-high energy (UHE) . The nature of these sources is still not well understood; therefore, astronomers are constantly searching for new objects of this type to characterize them, which could shed more light on their properties in general.

A team of astronomers led by University of Maryland’s Sajan Kumar decided to take a closer look at one such UHE gamma-ray source designated LHAASO J2108+5157. It is a point-like source with an extension less than 0.39 degrees, known to be associated with the [MML2017]4607—located some 10,700 away.

Computing is at an inflection point. Moore’s Law, which predicts that the number of transistors on an electronic chip will double about every two years, is slowing down due to the physical limits of fitting more transistors on affordable microchips. Increases in computer power are slowing down as the demand grows for high-performance computers that can support increasingly complex artificial intelligence models.

This inconvenience has led engineers to explore new methods for expanding the computational capabilities of their machines, but a solution remains unclear.

Photonic computing is one potential remedy for the growing computational demands of models. Instead of using transistors and wires, these systems utilize photons (microscopic light particles) to perform computation operations in the analog domain.

Not everyone uses their bicycle at night, but for those that do, safety is key! You’ve probably already have a bicycle helmet, a bicycle safety light and reflectors, but what about seeing the road/path in front of you. Well, this ingenious invention helps map the terrain changes in front of you while you’re riding. It’s called Lumigrids, and it’s essentially a mini projector that you mount on the front of your bicycle handlebars, and it places a grid of laser lights in front of you, mapping any terrain changes such as bumps, curbs, potholes, and more, to make it easy for you to see and maneuver around them.

The creators of the Lumigrids bicycle grid projection light claims that its an improvement over regular bicycle lights which cast shadows over ridges, bumps, and concaves which make it harder to for the bike rider to react properly to the terrain in front of them. Since the Lumigrids projecting light uses a grid system, it makes it much easier to identify issues with the terrain in front of you whether a spot is concaved, convexed, etc. If lines on the grid don’t line up properly, you’ll know there’s something in front of you.

You can change the settings of the bicycle grid projector to emit a larger or smaller sized grid depending on your needs, including a small grid for single bicycle usage at lower speeds, a higher speed setting for single bicycle usage which emits a larger grid, as well as an extra large grid that measures for use with multiple bikers.

If you thought ChatGPT was impressive, you ain’t seen nothing yet…

DeepMind co-founder Mustafa Suleyman predicts ongoing, exponential progress in LLMs and other generative AI. But the emergence of such powerful technology raises huge ethical and safety concerns.


DeepMind co-founder Mustafa Suleyman predicts that AI will continue its exponential progress, with orders-of-magnitude growth in model training sizes over the next few years.

Researchers from the University of Warsaw’s Faculty of Physics, in collaboration with experts from the QOT Centre for Quantum Optical Technologies, have pioneered an innovative technique that allows the fractional Fourier Transform of optical pulses to be performed using quantum memory.

This achievement is unique on the global scale, as the team was the first to present an experimental implementation of the said transformation in this type of system. The results of the research were published in the prestigious journal Physical Review Letters.

Physical Review Letters (PRL) is a peer-reviewed scientific journal published by the American Physical Society. It is one of the most prestigious and influential journals in physics, with a high impact factor and a reputation for publishing groundbreaking research in all areas of physics, from particle physics to condensed matter physics and beyond. PRL is known for its rigorous standards and short article format, with a maximum length of four pages, making it an important venue for rapid communication of new findings and ideas in the physics community.

In the study, published today in Science Translational Medicine, the researchers used engineered CAR T cells to target CD45—a surface marker found on nearly all blood cells, including nearly all blood cancer cells. Because CD45 is found on healthy blood cells too, the research team used CRISPR base-editing to develop a method called “epitope editing” to overcome the challenges of an anti-CD45 strategy, which would otherwise result in low blood counts, with potentially life-threating side effects. The early results represent a proof-of-concept for epitope editing, which involves changing a small piece of the target CD45 molecule just enough so that the CAR T cells don’t recognize it, but it… More.


A broad new strategy could hold hope for treating virtually all blood cancers with CAR T cell therapy, which is currently approved for five subtypes of blood cancer. A new preclinical, proof-of-concept study details the “epitope-editing” approach.

If people remember how sampling changed music, watch what this guys does to make AI music. A long time ago when people said AI will replace musicians, I replied AI is just a sampler. If people use a Tupac voice on a song like this guy did, they just pay royalties. Then with samplers arists made sample disks royalty free. They make money when you buy the sample disk. The same with AI, you just upload your sample disk into your AI, whether the music AI is from Meta or Google. Yeah Meta has music AI, you can see it used here.


Welcome to a showcase of sounds sampled through the power of artificial intelligence. Gone are the days of vinyl digging; now, we embrace prompt digging…

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Colab Notebook META AudioGen & MusicGEN:

PHILADELPHIA—Trying to finish your homework while the big game is on TV? “Visual-movement” neurons in the front of your brain can help you stay focused, according to a new study from neuroscientists in the Perelman School of Medicine at the University of Pennsylvania.

In the study, published recently in Neuron, the scientists sought to illuminate the neural mechanism that helps the brain decide whether to focus visual attention on a rewarding task or an alluring distraction. By analyzing neuron activity in animal models as they faced this kind of attentional conflict, the researchers discovered that a pattern of coordinated activity called “beta bursts” in a set of neurons in the lateral prefrontal cortex (LPFC)—a section in the front of the brain responsible for motivation and rewards—appears to have a major role in keeping attention task-focused, essentially by suppressing the influence of the distracting stimulus.

“Our research suggests that while all brains have the ability to focus on a rewarding task and filter out distractions, some are better at it than others,” said senior author Bijan Pesaran PhD, the Robert A Groff II Professor of Neurosurgery at Penn Medicine. “By understanding how our brains process rewarding stimuli, we hope to be able to also understand failures to do so in a variety of cognitive and psychiatric disorders, including attention deficit disorder, schizophrenia, and obsessive-compulsive disorder.”