Lifeboat Foundation: Safeguarding Humanity
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Researchers led by Hiroshi Ohno at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have discovered a new way to reduce obesity. Their study shows that supplying the gut with extra acetate reduces fat and liver mass in both normal and obese mice, as long as bacteria of the Bacteroides species are also present in the gut.

When both these conditions are met, gut bacteria can eliminate more sugars from the gut and promote the burning of fats for energy in the host. The findings were published in Cell Metabolism.

Affecting hundreds of millions of people around the world, obesity constitutes a global epidemic. It is linked to eating too much sugar and starchy foods and is known to increase the risk of heart disease, type-2 diabetes, and cancer. At the same time, studies show that eating fiber reduces the risk of these very same diseases—even though it cannot be digested directly by mammals.

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The global EUV Photoresists market is projected to grow from US$176.19 million in 2024 to US$646.71 million by 2030, at a Compound Annual Growth Rate (CAGR) of 24.20% during the forecast period.

In terms of production side, this report researches the EUV Photoresists production, growth rate, market share by manufacturers and by region (region level and country level), from 2022 to 2024, and forecast to 2030.

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IN A NUTSHELL 🚀 The PHARAO mission will launch an atomic clock to the International Space Station to test Einstein’s theory of general relativity. ⏰ This clock aims to measure time with unprecedented precision, detecting variations even at levels equivalent to a one-meter altitude change. 🔬 Advances in atomic clock technology, including laser-cooling techniques, enhance

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The brainwaves of people with neuropathic pain show a distinct pattern: more slow theta waves, fewer alpha waves, and more fast, high beta waves, co-lead author Sylvia Gustin, a clinical psychologist and UNSW professor, said in the statement. Her research has investigated changes in the thalamus—a central brain structure that relays sensory and motor signals to the cerebral cortex—associated with nerve pain.

The PainWaive system consists of an electroencephalogram (EEG) headset that records brain activity paired with an app that instructs patients on how to control their brainwaves through neurofeedback games, according to a UNSW statement. Four participants who suffer from corneal neuropathic pain—a condition that causes painful hypersensitivity of the eyes, face, or head—underwent 20 PainWaive sessions over the course of four weeks.

This study offers new hope for drug-free pain treatments, but further trials will need to verify its results.

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Many different cancer treatments work to directly target the tumor or the cells around it. The immediate goal is to mitigate growth and progression, with the hope of complete eradication and long-term durable immunity. However, many barriers prevent complete treatment efficacy. Different proteins and molecules secreted by the tumor polarize the environment around it to allow tumor progression. Unfortunately, the tumor generates an advantageous environment that not only suppresses the immune system, but also dysregulates immune cells to promote the spread of cancer.

Different immune cells around the tumor, such as neutrophils, macrophages, T cells, dendritic cells, and others normally work together to elicit a robust immune response. In the context of cancer, these cells take on a pro-tumor function or are prevented from executing their function. In response, many immunotherapies work to re-activate T cells, which are responsible for eliminating infected cells. Other cancer treatments, such as chemotherapy, works to directly kill the tumor.

While various therapies work through different biological mechanisms, it is still unclear how the tumor uses nutrients to fuel its progression and block immune cell response. Metabolism is the action of a cell that builds and breaks down molecules to provide energy. In general, it has been widely accepted that tumors rely on a metabolic process known as glycolysis to fuel its mass proliferation of cells. Specifically, cells breakdown glucose for energy. Although cancer cells gain energy through glycolysis, there is still a lot that is unclear about cellular metabolism and the influence it has on the environment around the tumor.

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