You can try out Portalgraph VR projection yourself with Unity.
Media conglomerate Ziff Davis claims ChatGPT creator has used their works for AI development.
It’s easy to solve a 3×3 Rubik’s cube, says Shantanu Chakrabartty, the Clifford W. Murphy Professor and vice dean for research and graduate education in the McKelvey School of Engineering at Washington University in St. Louis. Just learn and memorize the steps then execute them to arrive at the solution.
Computers are already good at this kind of procedural problem solving. Now, Chakrabartty and his collaborators have developed a tool that can go beyond procedure to discover new solutions to complex optimization problems in logistics to drug discovery.
Chakrabartty and his collaborators introduced NeuroSA, a problem-solving neuromorphic architecture modeled on how human neurobiology functions, but that leverages quantum mechanical behavior to find optimal solutions—guaranteed—and find those solutions more reliably than state-of-the-art methods.
Combinatorial Optimization problems can be solved by investigating the ground states of particular Ising models. Here, the authors developed a neuromorphic architecture to ensure asymptotic convergence to the ground state of an Ising problem and to consistently produce high-quality solutions.
A new study highlights a potential role for immune system dysfunction in the onset and progression of Alzheimer’s disease.
A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system’s response to cancer.
Blocking the activity of the protein turns formerly “cold,” or immune-resistant, liver tumors in mice into “hot” tumors teeming with cancer-fighting immune cells. When combined with an immunotherapy that further activates these immune cells against the cancer, the treatment led to complete regression of existing liver tumors in most mice. Treated animals lived for the duration of the experiment. In contrast, control animals survived only a few weeks.
“This is a fundamental breakthrough in our understanding of how the immune system is turned off and on in cancer,” said the senior author published the work in Science. “I could not be more excited about this discovery, and I hope treatments that target the mechanism we uncovered will quickly move forward to human trials.”
To understand what drives disease progression in tissues, scientists need more than just a snapshot of cells in isolation—they need to see where the cells are, how they interact, and how that spatial organization shifts across disease states. A computational method called MESA (Multiomics and Ecological Spatial Analysis), detailed in a study published in Nature Genetics, is helping researchers study diseased tissues in more meaningful ways.
The work details the results of a collaboration among researchers from MIT, Stanford University, Weill Cornell Medicine, the Ragon Institute of MGH, MIT, and Harvard, and the Broad Institute of MIT and Harvard, and was led by the Stanford team.
MESA brings an ecology-inspired lens to tissue analysis. It offers a pipeline to interpret spatial omics data—the product of cutting-edge technology that captures molecular information along with the location of cells in tissue samples. This data provides a high-resolution map of tissue “neighborhoods,” and MESA helps make sense of the structure of that map.
A new study of light anomalies combined with results from a Korea Microlensing Telescope Network microlensing survey show that super-Earths exist as far from their host star as our gas giants are from the sun. Which means that Earth-like exoplanets are a lot more common NASA press releases over every new statistical wobble suggest.
In a demographically diverse sample of healthy people, Cornell researchers found dramatic changes over the human lifespan in the brain’s “blue spot”—a tiny region involved in cognition and believed to be the first affected by neurodegenerative conditions including Alzheimer’s disease.
Using specialized MRI scans to measure the intensity of neuromelanin, a pigment that gives the locus coeruleus (LC) its blue color, the research team observed an inverted U-shaped curve that peaked in later middle age before dropping off sharply, a finding that helps characterize healthy aging patterns.
Maintaining a stronger blue signal after age 60 was associated with better cognitive performance, according to the study involving 134 participants aged 19 to 86. Because of the participants’ diversity, including about 40% who were non-white, the researchers also discovered higher peaks among Black participants and women, groups known to be more susceptible to Alzheimer’s.
On this day, April 25, in 1929, the world learned how astronomer Edwin Hubble had discovered that the universe was much larger than we had believed. On this day in 2025, you can preorder a book and on the 29th learn about this and four other Astrophysics discoveries that changed how we see the universe — and ourselves — in The Story of Astrophysics in Five Revolutions.
By Ersilia Vaudo, translated by Vanessa Di Stefano. If you use this link we get a penny or something.
He had published his seminal paper in the March issue of Astrophysical Journal but on April 25th in Proceedings of the National Academy of Sciences he published the how, and people began to think about what it meant. He had discovered that the collection of gas and dust we call Andromeda was actually another galaxy.