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The Era of Experience & The Age of Design: Richard S. Sutton, Upper Bound 2025
In his first large-scale public presentation after receiving the Turing Award, Dr. Richard S. Sutton presents, “The Era of Experience & The Age of Design,” r…
Ultrafast coherent dynamics of microring modulators
An ultra-compact, ultra-wide-bandwidth in-phase/quadrature modulator on a silicon chip is demonstrated, enabling coherent transmission for symbol rates up to 180 Gbaud and a net bit rate surpassing 1 Tb s−1 over an 80 km span, with modulation energy consumption as low as 10.4 fJ bit−1, and promising enhanced performance and scalability for future networking infrastructures.
Marine fungi degrade plastic and can be conditioned to do it faster
Plastics are a prevalent and persistent pollutant in the environment. As plastic production increases, finding ways to degrade these recalcitrant polymers is paramount. Many terrestrial fungi, across the kingdom, degrade various types of plastic. Plastics are the fastest-growing habitat in the oceans, and we hypothesized that fungi isolated from the ocean would demonstrate high success rates in degrading polyurethane (PU). To test this, visual degradation assays were performed by inoculating 1% PU medium with 68 different fungal strains cultured from marine habitats. The area of clearance of the fungus was measured periodically, to determine a relative degradation rate. Of the 68 fungal strains, 42 demonstrated the ability to degrade PU.
Brain Abnormality in Modern Humans Linked to Ancient Neanderthal DNA
Significant brain defects known as Chiari malformations could be down the genes some of us have inherited from Neanderthals, according to a new study, causing a mismatch between brain shape and skull shape.
The study focuses on Chiari malformation type I (CM-I), where the lower part of the brain extends too far into the spinal cord – typically linked to having a smaller-than-normal occipital bone at the back of the skull. It can lead to headaches, neck pain, and more serious conditions, and is thought to affect up to 1 in 100 people.
Several other ancient human species had different skull shapes to our own, and a previous study published in 2013 put forward the idea that interbreeding between Homo sapiens and these other hominins may be a root cause of Chiari malformation type I (CM-I), the mildest type of the group.
Escaping ageing through Cell Annealing—a phenomenological model
Memczak, S., Izpisua Belmonte, J.C. & Graepel, T. Escaping ageing through Cell Annealing—a phenomenological model. Cell Res (2025). https://doi.org/10.1038/s41422-025-01138-z.
