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Summary: Scientists used mathematics to explain the social phenomenon of six degrees of separation.

Their work suggests that the balance between the cost and benefit of maintaining social connections shapes the global human social network. According to their findings, individual efforts to optimize their social connections result in an average of six steps between any two people.

This explains why ideas, trends, and even diseases can spread globally within a few transmission steps.

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Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with non-alcoholic steatohepatitis (NASH)-related fibrosis.

The results, published in the June 24, 2023, online edition of The New England Journal of Medicine, found that a drug that mimics a hormone in the body improved both , or scarring of the , and liver inflammation in patients with NASH.

“Identifying an effective drug for NASH is extremely promising for patients as currently there are no FDA-approved therapies for this condition,” said Rohit Loomba, MD, the study’s first author and chief of the Division of Gastroenterology and Hepatology at UC San Diego School of Medicine. “NASH can adversely impact the quality of life in patients and can progress to . Its complications can lead to death or liver transplantation. Our findings will further the science of this disease and provide a potential new treatment option to those affected by NASH-related fibrosis.”

Artificial intelligence, including the most popular form at the moment, generative AI such as OpenAI’s ChatGPT, is going to provide tremendous leverage to software developers and make them vastly more productive, according to the chief technologist of MongoDB, the document database maker.


AI, especially the generative sort, is going to “let developers write code at the quality and the speed and the completeness that we’ve always wanted to,” says Mark Porter.

But a twist to her romantic narrative made it even more intriguing. Aria was describing in vivid detail her unique relationship with ChatGPT, the OpenAI-designed intelligent chatbot that has taken the world by storm with its near-human responses.

Across China, such unconventional bonds reflect a rising trend where individuals seek solace and companionship in AI-powered entities. In recent months, similar accounts on multiple social media platforms have sparked widespread debate over the implications of relying on AI for emotional connection and the potential risks associated with privacy and real-life relationships.

Most stroke patients taking the anticoagulant warfarin were no more likely than those not on the medication to experience a brain bleed when undergoing a procedure to remove a blood clot, UT Southwestern Medical Center researchers report in a new study. The findings, published in JAMA, could help doctors better gauge the risk of endovascular thrombectomy (EVT), potentially expanding the pool of eligible patients for this mainstay stroke treatment.

Warfarin is a type of blood thinner commonly used to prevent stroke because of heart conditions such as atrial fibrillation. Although not very common, patients taking may still experience a stroke. In , it’s very possible that some physicians may withhold an endovascular thrombectomy because patients have been treated with warfarin before their strokes.

Our study could increase the number of patients for whom this lifesaving and function-saving surgery would be appropriate, said study leader Ying Xian, M.D., Ph.D., Associate Professor of Neurology and in the Peter O’Donnell Jr. School of Public Health at UT Southwestern. Dr. Xian is also Section Head of Research, Stroke and Cerebrovascular Diseases in the Department of Neurology at UTSW.