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Astronomers have discovered a new type of stellar object that could change their understanding of extreme celestial bodies in the universe.

Initially, Curtin University doctoral student Tyrone O’Doherty spotted a spinning celestial space object in March 2018. The unfamiliar object released giant bursts of energy and beamed out radiation three times per hour.

In those moments, it became the brightest source of radio waves viewable from Earth through radio telescopes, acting like a celestial lighthouse.

A natural sugar called mannose is a type of hexose that is abundant in many different types of fruits. Recent studies have demonstrated that mannose has been found to be effective in promoting immune tolerance, suppressing inflammatory diseases, and efficient in suppressing tumors by suppressing glycolysis. However, it is not fully understood how mannose exerts its anticancer activity. Now, a study by Sanford Burnham Prebys and the Osaka International Cancer Institute has shed new light on the anticancer properties of mannose and suggests that mannose could be a helpful secondary treatment for cancer.

The findings are published in eLife in an article titled, “Metabolic clogging of mannose triggers dNTP loss and genomic instability in human cancer cells.”

“Mannose has anticancer activity that inhibits cell proliferation and enhances the efficacy of chemotherapy,” wrote the researchers. “How mannose exerts its anticancer activity, however, remains poorly understood. Here, using genetically engineered human cancer cells that permit the precise control of mannose metabolic flux, we demonstrate that the large influx of mannose exceeding its metabolic capacity induced metabolic remodeling, leading to the generation of slow-cycling cells with limited deoxyribonucleoside triphosphates (dNTPs).”

Patients who come to any Northwestern Medicine location for colonoscopies now have access to advanced artificial intelligence (AI) technology, which is improving the way gastroenterologists detect colon polyps and prevent colorectal cancer. According to new research by Northwestern Medicine, physicians who performed colonoscopies assisted by AI achieved a 13% increase in the detection and removal of colorectal polyps.

Computer-aided colonoscopies could reduce future colon cancer diagnoses by up to 39%.

“Most polyps do not become cancerous, but nearly all colorectal cancers begin as polyps,” says Rajesh N. Keswani, MD, MS, director of Endoscopy for Northwestern Memorial Hospital and director of quality for the Northwestern Medicine Digestive Health Center. “We want to detect them in their earliest stages and remove them to prevent future diagnoses of cancer. There’s nothing better than telling a patient that their decision to have a screening colonoscopy may have saved their life.”

We often discuss clinical trials, research studies that evaluate the efficacy of new medical approaches. Necessary for both improving healthcare and advancing medicine, clinical trials make up a vital part of the medical process. Here, we will begin a series of articles to provide an overview of the clinical trial process, which will help you understand all the exciting studies you read about!

Doctors and researchers use clinical trials to develop new drugs to treat cancer (or other diseases). What may be a surprise is that not all clinical trials aim to cure disease; some work to improve the quality of life for patients living with an illness. Clinical trials can also help us improve screening and diagnostic methods. Additionally, some clinical trials access new approaches for preventing disease.

Arguably the most crucial component of any clinical trial is the volunteers. Clinical trial participants may have the disease in question, but this isn’t always the case because some clinical trials rely on healthy volunteers.

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Our search for extraterrestrial life assumes alien life based on water and carbon, but could there be biochemistries based on other substances?

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