A new study from Karolinska Institutet, published in Nature Communications, reveals how rhythmic brain waves known as alpha oscillations help us distinguish between our own body and the external world. The findings offer new insights into how the brain integrates sensory signals to create a coherent sense of bodily self.
What makes you feel that your hand is yours? It might seem obvious, but the brain’s ability to tell self from non-self is a complex process.
Using a combination of behavioral experiments, brain recordings (EEG), brain stimulation, and computational modeling with a total of 106 participants, researchers from Karolinska Institutet investigated how the brain combines visual and tactile signals to create the feeling that a body part belongs to oneself—a phenomenon known as the sense of body ownership.
As we age, we don’t recover from injury or illness like we did when we were young. But new research from UCSF has found gene regulators—proteins that turn genes on and off—that could restore the aging body’s ability to self-repair.
The scientists looked at fibroblasts, which build the scaffolding between cells that give shape and structure to our organs.
Fibroblasts maintain this scaffolding in the face of normal wear, disease, and injury. But over time, they slow down, and the body suffers.
In this quality improvement project, nonmydriatic ocular fundus imaging enabled prompt and accurate rule-out of papilledema in patients with headaches presenting to the emergency department and facilitated rapid and reliable examination of the ocular fundus.
Huang made his feelings about AI skeptics, haters, and doom-mongers clear on a recent episode of the No Priors podcast.
The boss of the world’s most valuable company said “the battle of the narratives” between those who think AI will benefit society and those who believe it will degrade or even destroy it was one of his biggest takeaways from 2025.
Huang did admit that “it’s too simplistic” to dismiss either of these views entirely, but he believes some naysayers’ views are having a detrimental effect.
This video explores aliens, mind uploading to other species, genetic engineering, and future robots.
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💡 Future Business Tech explores the future of technology and the world.
Examples of topics I cover include: • Artificial Intelligence & Robotics. • Virtual and Augmented Reality. • Brain-Computer Interfaces. • Transhumanism. • Genetic Engineering.
This video explores the future of ChatGPT and 10 ways it could change society. Other related terms: aliens, alien species, advanced civilization, genetic engineering, robot, mind upload, mind uploading, brain computer interface, artificial intelligence, ai, future business tech, future technology, future technologies, etc.
Dartmouth researchers conducted the first-ever clinical trial of a generative AI-powered therapy chatbot and found that the software resulted in significant improvements in participants’ symptoms, according to results published March 27 in NEJM AI.
People in the study also reported they could trust and communicate with the system, known as Therabot, to a degree that is comparable to working with a mental health professional.
The trial consisted of 106 people from across the United States diagnosed with major depressive disorder, generalized anxiety disorder, or an eating disorder. Participants interacted with Therabot through a smartphone app by typing out responses to prompts about how they were feeling or initiating conversations when they needed to talk.
A recent publication in Nature Medicinedescribes a novel immunotherapy targeting pancreatic cancer that has shown promising results in a first in-human phase 1/2 trial.
The TACTOPS trial, which investigated the safety and clinical effects of autologous T cell therapy targeting multiple tumor antigens, was a collaboration among researchers at Baylor College of Medicine, the Dan L Duncan Comprehensive Cancer Center, the Center for Cell and Gene Therapy, Texas Children’s Hospital and Houston Methodist Hospital.
“We wanted to develop a targeted therapeutic that would hone the immune system on tumor-associated antigens (TAAs) that were present on malignant cells. We targeted five different antigens to deal with the polyclonal nature of the disease,” said co-corresponding author Dr. Ann Leen, professor of pediatrics–hematology and oncology in the Center for Cell and Gene Therapy.
This study represents a characterization of pediatric Charcot-Marie-Tooth disease in a Canadian cohort and demonstrates that disease onset, severity, and manifestations are highly variable even in childhood.
For this study, the researchers focused on a type of colorectal cancer that accounts for 80% to 85% of all colorectal cancers — microsatellite stable (MSS) with proficient mismatch repair (MMRp), meaning the tumors’ DNA is relatively stable. These cancers are largely resistant to checkpoint inhibitor immunotherapies.
Previous groundbreaking research found checkpoint inhibitors alone could successfully treat rectal cancer and several other cancers with the opposite tumor type — those with high microsatellite instability (MSI-H) and mismatch repair deficiency (MMRd). This allows doctors to spare many patients from surgery, chemotherapy, and radiation.
Here the team employed an mouse model that accurately recreates the common mutations, behaviors, and immune cell composition of human colorectal cancer. They found that the regulatory T cells associated with the cancer are split between two types: Cells that make a signaling molecule (cytokine) called interleukin‑10 (IL-10) and cells that don’t.
Through a series of sophisticated experiments that selectively eliminated each type of cell, the researchers discovered:
When IL-10-positive cells were removed, tumor growth accelerated.
In most solid tumors, high numbers of regulatory T (Treg) cells are associated with poorer outcomes because they dampen the immune system’s ability to fight against a tumor.
