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MRI study reveals structural brain changes in children with restrictive eating disorders

In the last decade, the incidence of restrictive eating disorders in children, like anorexia-nervosa and avoidant/restrictive food intake disorders (ARFID), has doubled. These disorders have severe consequences for growing children, resulting in nutritional deficiencies and problems with bone development, statural growth and puberty. Most studies have focused on the effects of these disorders in older individuals, and little is currently known about how restrictive eating disorders affect the brain in children or what mechanisms in the brain might be responsible for this restrictive eating behavior.

To get a better understanding of how these early-onset eating disorders work in the brain, researcher Clara Moreau and her team conducted MRI brain scans on 290 , of which 124 had been hospitalized for early-onset anorexia-nervosa (EO-AN), 50 had been hospitalized for ARFID, and 116 were children with no eating disorders. All participants were under 13 years old, and those who were hospitalized had very low body mass index (BMI) due to restrictive eating. The results were published in Nature Mental Health.

Although EO-AN and AFRID both result in low BMI and malnutrition due to restrictive eating, they are distinct disorders. EO-AN—as well as later onset anorexia-nervosa—is characterized by restrictive eating arising from a distorted body image, while restrictive eating in AFRID arises from sensory issues, such as a dislike of certain food textures, a lack of interest in food or fear of negative health consequences from food. These differences indicate that the disorders probably arise from different mechanisms in the brain.

Smarter silicone bonding enables engineering of stronger soft devices

In a step forward for soft robotics and biomedical devices, Rice University engineers have uncovered a powerful new way to boost the strength and durability of silicone-based soft devices without changing the materials themselves. Their study, published in a special issue of Science Advances, focuses on printed and musculoskeletal robotics and offers a predictive framework that connects silicone curing conditions with adhesion strength, enabling dramatic improvements in performance for both molded and 3D-printed elastomer components.

Where did all the antimatter go? This mismatch in how subatomic particles behave could hold a clue

The first-known observations of matter–antimatter asymmetry in a decaying composite subatomic particle that belongs to the baryon class are reported from the LHCb experiment located at the Large Hadron Collider at CERN. This effect, known as charge–parity (CP) violation, has been theoretically predicted, but hitherto escaped observation in baryons. The experimental verification of this asymmetry violation in baryons, published in Nature this week, is important as baryons make up most of the matter in the observable universe.

Cosmological models suggest that matter and antimatter were created in equal amounts at the Big Bang, but in the present-day universe matter seems to dominate antimatter. This imbalance is thought to be driven by differences in the behavior of matter and antimatter: a violation of symmetry known as CP violation.

This effect has been predicted by the Standard Model of physics and observed experimentally in subatomic particles called mesons more than 60 years ago, but never previously observed in baryons. As opposed to mesons, which are formed by two quarks, baryons are formed by three quarks—particles that make up most of matter such as neutrons and protons are baryons.

Robots now grow and repair themselves by consuming parts from other machines

Today’s robots are stuck—their bodies are usually closed systems that can neither grow nor self-repair, nor adapt to their environment. Now, scientists at Columbia University have developed robots that can physically “grow,” “heal,” and improve themselves by integrating material from their environment or from other robots.

Described in a new study published in Science Advances, this process, called “Robot Metabolism,” enables machines to absorb and reuse parts from other robots or their surroundings.

“True autonomy means robots must not only think for themselves but also physically sustain themselves,” explains Philippe Martin Wyder, lead author and researcher at Columbia Engineering and the University of Washington. “Just as absorbs and integrates resources, these robots grow, adapt, and repair using materials from their environment or from other robots.”