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The UK is developing a controversial AI tool to predict potential murderers using personal data from convicts, victims, and witnesses. Aimed at preventing crime, the initiative mirrors global trends in AI policing. However, critics warn of bias, privacy issues, and call the project “chilling and dystopian,” raising ethical concerns about pre-crime technology.

UK | artificial intelligence | AI | murder | firstpost | world news | news live | vantage | palki sharma | news.

#uk #ai #murder #firstpost #vantageonfirstpost #palkisharma #worldnews.

Vantage is a ground-breaking news, opinions, and current affairs show from Firstpost. Catering to a global audience, Vantage covers the biggest news stories from a 360-degree perspective, giving viewers a chance to assess the impact of world events through a uniquely Indian lens.

The show is anchored by Palki Sharma, Managing Editor, Firstpost.

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There was the hype, then the testing, now companies are deploying artificial intelligence at the heart of their operations. We ask one of the world’s most prominent AI scientists for his advice for companies, and hear how Siemens is creating the ‘brains’ to run the factories of the future.

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How does the brain work? Where, and when, and why do neurons connect and send their signals? Scientists have created the largest wiring diagram and functional map of an animal brain to date to learn more. Research teams at Allen Institute, @BCMweb and @princeton worked together to map half a billion synapses, over 200,000 cells, and 4km of axons from a cubic millimeter of mouse brain, providing unparalleled detail into its structure and functional properties. The project is part of the Machine Intelligence from Cortical Networks (MICrONS) program, which seeks to revolutionize machine learning by reverse-engineering the algorithms of the brain. Research findings reveal key insights into brain activity, connectivity, and structure—shedding light on both form and function—within a region of the mouse visual cortex that plays a critical role in brain health and is often disrupted in neurological conditions such as Alzheimer’s disease, autism, and addiction. These insights could revolutionize our ability to treat neuropsychiatric diseases or study the influence of drugs and other changes on the brain.

This extraordinary achievement begins to reveal the elusive language the brain uses to communicate amongst its millions of cells and the cortical mechanisms of intelligence—one of the holy grails of science.

Learn more about this research: https://alleninstitute.org/news/scien… open science data: https://www.microns-explorer.org/ Explore the publications in Nature: https://www.nature.com/immersive/d428… Follow us on social media: Bluesky — https://bsky.app/profile/alleninstitu… Facebook — / alleninstitute X — / alleninstitute Instagram — / alleninstitute LinkedIn — / allen-institute TikTok — / allen.institute.
Access open science data: https://www.microns-explorer.org/
Explore the publications in Nature: https://www.nature.com/immersive/d428…

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To survey the real-world effectiveness and cost of optic nerve sheath meningioma (ONSM) treating with Gamma Knife Radiosurgery (GKRS), and compare with the external beam radiation therapy (EBRT).

Retrospective, comparative study that included patients with primary ONSM treated with either GKRS or EBRT in Samsung Medical Center, Korea. The treatment response, and treatment costs were compared between GKRS and EBRT groups.

There were 34 adult patients with primary ONSM treated with either GKRS (n = 25) or EBRT (n = 9) (follow-up period: 6–207 months). The local tumor control rates (GKRS: 92%; EBRT: 100%; P = 1) and vision preservation rates (GKRS: 64%; EBRT: 67%; P = 1) were similar in both groups. The mean gross tumor volume (GTV) decreased by 21.4 ± 19.7% after GKRS and 26.4 ± 18.7% after EBRT (P = 0.4803). The complication rates did not differ between two modalities. Factors associated with better visual outcomes were pretreatment BCVA 20/50 (odds ratio: 6.000, P = 0.0234) and the absence of intracranial tumor extension (odds ratio: 30.00, P = 0.0001). GKRS reduced the total costs of care by 43% under Korean National Health Insurance System (NHIS).

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Nexus between genomic instability and metabolism in cancer.

Genomic damage detection and repair in the cells is enabled by the DNA-damage response (DDR).

Although DDR inhibition has been used to treat various cancers, drug resistance has been observed in the long run owing to the ability of tumor cells to undergo energetic metabolic reprogramming.

In addition, tumor cells’ ability to sense oxidative stress influenced by metabolic intermediates, leading to impaired redox metabolism, thus creating redox vulnerabilities.

The researchers in this review summarize recent advances in understanding the crosstalk between DDR and metabolism and discuss combination therapies that target DDR, metabolism, and redox vulnerabilities in cancer.

They also outline challenges in targeting metabolism and strategies to improve the shortcomings. https://sciencemission.com/Unraveling-the-nexus

Continue reading “Intestinal immune cell prevents food allergies” | >

Previous studies reported that the association between statins use and influenza infection was contradictory. A systematic review and meta-analysis of longitudinal studies were performed to determine the association between statins use and influenza susceptibility. The literature search was conducted in PubMed, Embase, and Web of Science, from each database’s inception to 21 May 2023. The fixed effect model and random effects model were used for data synthesis. In our study, a total of 1,472,239 statins users and 1,486,881 statins non-users from five articles were included. The pooled risk ratio (RR) of all included participants was 1.05 (95% CI: 1.03–1.07), and there were still significant differences after adjusting for vaccination status. Of note, RR values in statins users were 1.06 (95% CI: 1.03–1.08) in people aged ≥60 years old and 1.05 (95% CI: 1.03–1.07) in participant groups with a higher proportion of females. Administration of statins might be associated with an increased risk of influenza infection, especially among females and elderly people. For those people using statins, we should pay more attention to surveillance of their health conditions and take measures to prevent influenza infection.

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