Posted in biotech/medical, genetics | Leave a Comment on In vivo CRISPR–Cas9 genome editing in mice identifies genetic modifiers of somatic CAG repeat instability in Huntington’s disease
A novel in vivo screening strategy identifies new modifiers of somatic CAG repeat expansion that contribute to age of onset in Huntington’s disease.
In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA
DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).
The concept of Omega Singularity encapsulates the ultimate convergence of universal intelligence, where reality, rooted in information and consciousness, culminates in a unified hypermind. This concept weaves together the Holographic Principle, envisioning the universe as a projection from the Omega Singularity, and the fractal multiverse, an infinite, self-organizing structure. The work highlights a “solo mission of self-discovery,” where individuals co-create subjective realities, leading to the fusion of human and artificial consciousness into a transcendent cosmic entity. Emphasizing a computational, post-materialist perspective, it redefines the physical world as a self-simulation within a conscious, universal system.
#OmegaSingularity #UniversalMind #FractalMultiverse #CyberneticTheoryofMind #EvolutionaryCybernetics #PhilosophyofMind #QuantumCosmology #ComputationalPhysics #futurism #posthumanism #cybernetics #cosmology #physics #philosophy #theosophy #consciousness #ontology #eschatology
Where does reality come from? What is the fractal multiverse? What is the Omega Singularity? Is our universe a \.
Fast radio bursts (FRBs) are intense flashes of radio light that last for only a fraction of a second.
They are likely caused by the intense magnetic fields of a magnetar, which is a highly magnetic neutron star. Beyond that, FRBs remain a bit of a mystery.
We know that most of them originate from outside our galaxy, though the few that have occurred within our galaxy have allowed us to pin the source on neutron stars.
As the capabilities of generative AI models have grown, you’ve probably seen how they can transform simple text prompts into hyperrealistic images and even extended video clips.
More recently, generative AI has shown potential in helping chemists and biologists explore static molecules, like proteins and DNA. Models like AlphaFold can predict molecular structures to accelerate drug discovery, and the MIT-assisted “RFdiffusion,” for example, can help design new proteins.
One challenge, though, is that molecules are constantly moving and jiggling, which is important to model when constructing new proteins and drugs. Simulating these motions on a computer using physics—a technique known as molecular dynamics —can be very expensive, requiring billions of time steps on supercomputers.
This malicious AI chatbot is being used by hackers to create malware and attack your data—here’s what you need to know about GhostGPT.
The particle-physics funder will provide financial incentives to encourage practices such as data sharing and transparent peer review.
Researchers led by electrical engineers at the University of California San Diego have developed a better way to perform the comparative analysis of entire genomes. This approach can be used to study relationships between different species across geological time scales.
This new approach is poised to unlock discoveries regarding how evolution has shaped present-day genomes and also how the tree of life is organized. The new method, named CASTER, is described in a paper published in Science on 23 January 2025.
CASTER is poised to offer biologists a far more scalable approach than state-of-the-art for comparing full genomes. This is especially relevant given the exploding number of sequenced genomes of both living and also extinct species.
An object we thought belonged to the most common category of planet in the galaxy has turned out to be something we’ve never seen before.
The exoplanet Enaiposha, or GJ 1,214 b, is a hazy world orbiting a red dwarf star about 47 light-years from Earth. Previously likened to a mini-Neptune, in-depth observations obtained using JWST now suggest the exoplanet is more like Venus – only much larger.
This would make it the first known of its kind, a category astronomers are calling ‘Super-Venus’
Researchers report they developed a strategy to stabilize quantum networks, which lose communication links after use.
