Scientists said Wednesday that they had created an AI model able to predict medical diagnoses years in advance, building on the same technology behind consumer chatbots like ChatGPT.
Based on a patient’s case history, the Delphi-2M AI “predicts the rates of more than 1,000 diseases” years into the future, the team from British, Danish, German and Swiss institutions wrote in a paper published in the journal Nature.
Researchers trained the model on data from Britain’s UK Biobank – a large-scale biomedical research database with details on about half a million participants.
University of Oxford-led research finds low-dose rapamycin functions as a genomic protector in aging human immune cells, lowering DNA damage.
The mechanistic target of rapamycin (mTOR) is a central signaling pathway that regulates and coordinates cell growth, metabolism, and survival in response to environmental cues. It helps cells integrate signals from growth factors, nutrients, and stress to control whether they are in an anabolic (building up) or catabolic (breaking down) state.
Aging immune systems accumulate DNA damage linked to immunosenescence. Rapamycin is a drug that inhibits the mTOR pathway. Originally developed for organ transplantation to prevent immune rejection, previous research has found that, at non-immunosuppressive doses, rapamycin can mitigate cellular senescence.
University of Bristol astrophysicists are helping shed new light on an Earth-sized exoplanet 40 light years away where liquid water in the form of a global ocean or icy expanse might exist on its surface. That would only be possible if an atmosphere is present—a big mystery that the scientists are attempting to unravel and now even closer to solving using the largest telescope in space.
Deploying NASA’s JWST, the researchers have reached these discoveries as part of a major international project which is probing the atmosphere and surface of TRAPPIST-1e, also more simply known as planet e in the system, orbiting within the habitable zone of red dwarf star TRAPPIST-1.
Exoplanets are highly varied planets which orbit stars outside the solar system. Planet e is of particular interest because the presence of liquid water—not too hot or cold—is theoretically viable, but only if the planet has an atmosphere.
Interesting.
GRENOBLE, France – Sept. 16, 2025 – CEA-Leti and the Centre for Research on Heteroepitaxy and its Applications (CRHEA) today announced R&D results that have cleared a path toward full-color microdisplays based on a single material system, a long-standing goal for augmented and virtual reality (AR/VR) technologies.
The project, presented in a paper published in Nature Communications Materials, developed a technique for growing high-quality InGaN-based quantum wells on sub-micron nanopyramids, enabling native emission of red, green, and blue (RGB) light from a single material system. Titled “Regular Red-Green-Blue InGaN Quantum Wells With In Content Up To 40% Grown on InGaN Nanopyramids”, the paper will be presented at the MicroLED Connect Conference on Sept. 24, in Eindhoven, the Netherlands.
Microdisplays for immersive devices require bright RGB sub-pixels smaller than 10 × 10 microns. According to the paper, “the use of III-nitride materials promises high efficiency micro-light emitting diodes (micro-LEDs) compared to their organic counterparts. However, for such a pixel size, the pick and place process is no longer suitable for combining blue and green micro-LEDs from III-nitrides and red micro-LEDs from phosphide materials on the same platform.” Red-emitting phosphide micro-LEDs also suffer from efficiency losses at small sizes, while color conversion methods face challenges in deposition precision and stability.
Ji, J., Ye, Z., Wang, Z. et al. Light Sci Appl 14, 332 (2025). https://doi.org/10.1038/s41377-025-02014-6
Cadmium (Cd) is a metal with no nutritional value or physiological role. However, it is found in the body of most people because it is a contaminant of nearly all food types and is readily absorbed. The body burden of Cd is determined principally by its intestinal absorption rate as there is no mechanism for its elimination. Most acquired Cd accumulates within the kidney tubular cells, where its levels increase through to the age of 50 years but decline thereafter due to its release into the urine as the injured tubular cells die. This is associated with progressive kidney disease, which is signified by a sustained decline in the estimated glomerular filtration rate (eGFR) and albuminuria. Generally, reductions in eGFR after Cd exposure are irreversible, and are likely to decline further towards kidney failure if exposure persists.
This is a ~50-minute talk titled “Substrate-dependent mathematics hypothesis” by Olaf Witkowski (https://olafwitkowski.com/), presented for our Platonic Space symposium (https://thoughtforms.life/symposium-on-the-platonic-space/).