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Nano-bio interfaces for electrical and biochemical signal transduction

Nano-bio interfaces enable communication between synthetic materials and biological systems at the nanoscale, with their functionality shaped by material properties, surface chemistry and topography. This Review discusses the key considerations and methods for engineering nano-bio interfaces for bioelectrical signal detection and biochemical signal transduction.

Mutations Lurking in Alternative Proteins May Cause Disease

Although the genetic cause of many diseases have been identified, it’s estimated that as many as 70% of patients with a rare disorder do not know what causes their disease. Millions of people live with rare diseases, and scientists are still searching for the answers to these medical mysteries. Now researchers have developed a different method for analyzing patient genetic data, which may provide clues. These findings, which were reported in Molecular Cell, have highlighted that multiple proteins can often be produced from one gene; the cell can simply interpret the sequence in different ways.

In a basic genetics lesson, a student will learn that proteins are encoded by genes, and that different genes make different proteins. But in reality, the same gene sequence may encode for multiple proteins, and it can be up to the molecular machinery of the cell to decide which of those gene sequences ends up transcribed into a protein. In fact, most genes can code for more than one protein.

Iconic Andean monument may have been used for Indigenous accounting

Sediment analysis and drone photography of the iconic South American monument of Monte Sierpe (aka “Band of Holes”) support a new interpretation of this mysterious landscape feature as part of an Indigenous system of accounting and exchange.

Stretching 1.5 km across the Pisco Valley of the southern Peruvian Andes, Monte Sierpe (meaning serpent mountain) is a large row of approximately 5,200 precisely aligned holes (1–2 m wide and 0.5–1 m deep), organized into sections or blocks.

It first gained modern attention in 1933, when aerial photographs of the holes were published in National Geographic, but the monument’s purpose is still uncertain.

Thin resistor routinely used in photonic devices can also act as a thermometer

Integrated photonics has become a multi-billion-dollar industry, but it is feeling the heat—literally.

An increasingly important component in data centers, photonic devices move and process data using light instead of electricity. The physical nature of light gives this approach several advantages, including higher bandwidth and lower latency.

One limitation on even wider adoption has been the hardware’s sensitivity to temperature. If photonic devices become a little too hot or a little too cold, their exquisitely tuned photonic properties can be disrupted.

Diet Composition That Corresponds To A 17y Younger Biological Age (Test #6 In 2025 Deep Dive)

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What if the CMB Isn’t Actually Cosmic? — Dr. Patrick Vanraes, DemystifySci #380

The universe hums a low, steady note…or so we were told. Dr. Patrick Vanraes, a plasma physicist from the University of Antwerp, joins us in that quiet static, where light and truth blur at the edges. We talk of cosmic beginnings, instrument design, of warmth beneath the skies, of radio echoes mistaken for the birth of everything. In that hum, between curiosity and doubt, the cosmos seems to ask who’s really paying attention.

CORRECTION NOTE: Dr. Robitaille wishes it to be known that when he says \.

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