Lifeboat Foundation

Cancer cells delete DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

NASA’s former chief scientist on why space exploration is vital to humanity.

Humans are about to return to the Moon, and may go to Mars. An expert explains why space exploration is vital and can help us protect our ‘pale blue dot’.

Van Heurck et al. identify CROCCP2, a hominid-specific gene duplicate, as a human-specific modifier of neurogenesis in the developing cerebral cortex. They find that CROCCP2 is necessary and sufficient to enhance human cortical progenitor amplification and acts by decreasing primary cilia dynamics and enhancing the mTOR pathway.

Bohr’s model of the atom is kind of crazy. His collage of ideas mixing old and new concepts was the fruit of Bohr’s amazing intuition. Looking only at hydrogen, the simplest of all atoms, Bohr formed the image of a miniature solar system, with a proton in the center and the electron circling around it.

Following the physicist’s way of doing things, he wanted to explain some of his observed data with the simplest possible model. But there was a problem. The electron, being negatively charged, is attracted to the proton, which is positive. According to classical electromagnetism, the theory that describes how charged particles attract and repel one another, an electron would spiral down to the nucleus. As it circled the proton, it would radiate away its energy and fall in. No orbit would be stable, and atoms could not exist. Clearly, something new and revolutionary was needed. The solar system could only go so far as an analogy.

To salvage the atom, Bohr had to invent new rules that clashed with classical physics. He bravely suggested the implausible: What if the electron could only circle the nucleus in certain orbits, separated from each other in space like the steps of a ladder or the layers of an onion? Just like you can’t stand between steps, the electron can’t stay anywhere between two orbits. It can only jump from one orbit to another, the same way we can jump between steps. Bohr had just described quantum jumps.

We don’t need one Elon Musk. We need 8 billion empathic futurists.

Google’s Threat Analysis Group (TAG) has linked an exploit framework that targets now-patched vulnerabilities in the Chrome and Firefox web browsers and the Microsoft Defender security app to a Spanish software company.

While TAG is Google’s team of security experts focused on protecting Google users from state-sponsored attacks, it also keeps track of dozens of companies that enable governments to spy on dissidents, journalists, and political opponents using surveillance tools.

The search giant says the Barcelona-based software firm is one of these commercial surveillance vendors and not just a provider of custom security solutions as it officially claims.

As any weekend warrior understands, cartilage injuries to joints such as knees, shoulders, and hips can prove extremely painful and debilitating. In addition, conditions that cause cartilage degeneration, like arthritis and temporomandibular joint disorder (TMJ), affect 350 million people in the world and cost the U.S. public health system more than $303 billion every year. Patients suffering from these conditions experience increased pain and discomfort over time.

However, an exciting study led by faculty at The Forsyth Institute suggests new strategies for making cartilage cells with huge implications in regenerative medicine for future cartilage injuries and degeneration treatments. In a paper, entitled “GATA3 mediates nonclassical β-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis,” co-first authors Takamitsu Maruyama and Daigaku Hasegawa, and senior author Wei Hsu, describe two breakthrough discoveries, including a new understanding of a multifaced protein called β-catenin.

Dr. Hsu is a senior scientist at the Forsyth Insitute and a Professor of Developmental Biology at Harvard University. He is also an affiliate faculty member of the Harvard Stem Cell Institute. Other members conducting the study included Swiss scientists Tomas Valenta and Konrad Basler, and Canadian scientists Jody Haigh and Maxime Bouchard. The study appears in the most recent issue of Science Advances.

Future pets!

A new study finds surprising evidence of the self-evolution of urban foxes.

Pregnancy caused women to lose gray matter, and reshaped the brain’s “default mode network,” a set of brain regions that are most active when the brain is wandering.