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This is good news! The article says this could lead to treatment of other cancers.


A particularly aggressive form of childhood cancer that forms in muscle tissue might have a new treatment option on the horizon.

Scientists have successfully induced rhabdomyosarcoma cells to transform into normal, healthy muscle cells. It’s a breakthrough that could see the development of new therapies for the cruel disease, and it could lead to similar breakthroughs for other types of human cancers.

“The cells literally turn into muscle,” says molecular biologist Christopher Vakoc of Cold Spring Harbor Laboratory.

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Rohit Chikkaraddy/ University of Birmingham.

Mid-infrared, as the name suggests, lies between the infrared spectrum’s near and far wavelengths, just outside those of visible light. The mid-infrared spectrum has gained particular importance as it has been useful for multiple applications ranging from military to environmental and medical treatments and studying celestial objects.

1 Department of Biotechnology, School of Science, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, 530,045, India; 2 Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61,801, USA

Correspondence: Sireesha V Garimella; Pankaj Chaturvedi, Email [email protected]; [email protected]

Abstract: Cancer continues to rank among the world’s leading causes of mortality despite advancements in treatment. Cancer stem cells, which can self-renew, are present in low abundance and contribute significantly to tumor recurrence, tumorigenicity, and drug resistance to various therapies. The drug resistance observed in cancer stem cells is attributed to several factors, such as cellular quiescence, dormancy, elevated aldehyde dehydrogenase activity, apoptosis evasion mechanisms, high expression of drug efflux pumps, protective vascular niche, enhanced DNA damage response, scavenging of reactive oxygen species, hypoxic stability, and stemness-related signaling pathways. Multiple studies have shown that mitochondria play a pivotal role in conferring drug resistance to cancer stem cells, through mitochondrial biogenesis, metabolism, and dynamics. A better understanding of how mitochondria contribute to tumorigenesis, heterogeneity, and drug resistance could lead to the development of innovative cancer treatments.

Russia’s space agency on Tuesday said that the crew stuck on the International Space Station because of a damaged capsule were now expected to return to Earth in September, a year after they first launched into orbit.

Russian cosmonauts Dmitry Petelin and Sergei Prokopyev and NASA astronaut Frank Rubio flew to the ISS in September 2022 aboard a Soyuz MS-22 capsule.

They were scheduled to return home in the same spacecraft, but it began leaking coolant in mid-December after being hit by what US and Russian space officials believe was a tiny space rock.

A team of computer scientists at the University of Massachusetts Amherst, led by Emery Berger, recently unveiled a prize-winning Python profiler called Scalene. Programs written with Python are notoriously slow—up to 60,000 times slower than code written in other programming languages—and Scalene works to efficiently identify exactly where Python is lagging, allowing programmers to troubleshoot and streamline their code for higher performance.

There are many different —C++, Fortran and Java are some of the more well-known ones—but, in recent years, one language has become nearly ubiquitous: Python.

“Python is a ‘batteries-included’ language,” says Berger, who is a professor of computer science in the Manning College of Information and Computer Sciences at UMass Amherst, “and it has become very popular in the age of data science and because it is so user-friendly.” The comes with libraries of easy-to-use tools and has an intuitive and readable syntax, allowing users to quickly begin writing Python code.