Lifeboat Foundation: Safeguarding Humanity
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Blog – Page 2749

BARDA is part of the Administration for Strategic Preparedness and Response within the U.S. Department of Health and Human Services.

The NTxscribe platform is a cell-free, continuous flow manufacturing system that reportedly delivers scalable RNA (including mRNA and self-amplifying RNA) materials in a tabletop footprint. This enzymatic process is designed to provide a low cost and rapidly deployable, vertically integrated manufacturing system, according to Jamie Coffin, PhD, CEO of NTx. Through this program, the system is being evaluated for its express development of RNA vaccines and therapeutics for infectious diseases, as well as its capability for distributed biomanufacturing.

“The traditional batch processes for developing vaccines and other biologics are burdensome and cannot be scaled quickly in the event of an emergency,” said Coffin. “Over the course of this project, we will aim to prove that NTxscribe can help BARDA meet its goals toward decentralized and rapidly deployable vaccine manufacturing.”

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You could be walking around with an unruptured brain aneurysm. But don’t panic – the Brain Aneurysm Foundation estimates that about 1 in 50 people in the U.S. has an unruptured brain aneurysm. Director of Endovascular Neurosurgery Koji Ebersole, MD, says people are surprised to learn that the majority of aneurysms don’t cause any symptoms.

An aneurysm develops when a vessel in the brain has a thin spot, which then fills with blood, creating a bulge or balloon shape. Most brain aneurysms are small, about the size of a pea. Because the brain itself has no sensory fibers, there is no pain and the brain doesn’t register that the aneurysm is there.

“Most patients find out they have an aneurysm for a completely unrelated reason,” Dr. Ebersole says. “Maybe they’re having trouble with their sinuses and have a CT scan and the doctors find an aneurysm. When you learn you have an aneurysm, it’s important to meet with a physician who’s practiced in neurology to talk about the implications.”

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Can stem cells block organ transplant rejection?

Organ transplant patients traditionally go through a grueling journey post operation, which involves a copious amount of medication for life. After years of research, Dr. Jeffrey Veale has performed a first-of-its kind surgery that could entirely change the landscape for patients. Rudabeh Shahbazi reports.

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