Dr. Sung Mook Choi and his research team at the Energy & Environmental Materials Research Division of the Korea Institute of Materials Science (KIMS) have successfully developed a highly durable non-precious metal-based hydrogen evolution catalyst for use in a direct electrolysis system employing waste alkaline water and anion exchange membranes (AEM). This breakthrough enables the production of clean hydrogen by directly utilizing alkaline wastewater generated from industrial processes.
Crystals and glasses have opposite heat-conduction properties, which play a pivotal role in a variety of technologies. These range from the miniaturization and efficiency of electronic devices to waste-heat recovery systems, as well as the lifespan of thermal shields for aerospace applications.
The problem of optimizing the performance and durability of materials used in these different applications essentially boils down to fundamentally understanding how their chemical composition and atomic structure (e.g., crystalline, glassy, nanostructured) determine their capability to conduct heat. Michele Simoncelli, assistant professor of applied physics and applied mathematics at Columbia Engineering, tackles this problem from first principles — i.e., in Aristotle’s words, in terms of “the first basis from which a thing is known” — starting from the fundamental equations of quantum mechanics and leveraging machine-learning techniques to solve them with quantitative accuracy.
In research published on July 11 in the Proceedings of the National Academy of Sciences, Simoncelli and his collaborators Nicola Marzari from the Swiss Federal Technology Institute of Lausanne and Francesco Mauri from Sapienza University of Rome predicted the existence of a material with hybrid crystal-glass thermal properties, and a team of experimentalists led by Etienne Balan, Daniele Fournier, and Massimiliano Marangolo from the Sorbonne University in Paris confirmed it with measurements.
Quantum stochastic rectification is a process observed in some physical systems, which entails the conversion of random quantum fluctuations (i.e., quantum noise) and a small oscillating signal, such as a weak alternating current or AC voltage, into a steady output (e.g., a direct current, or DC). This quantum effect has been previously reported in magnetic tunnel junctions that are driven by both quantum mechanics and randomness (i.e., stochastic processes).
Researchers at the University of California–Irvine recently showed that the quantum stochastic rectification observed in individual molecules can be leveraged to study their intrinsic relaxation dynamics. Their approach, outlined in a paper published in Physical Review Letters, could inform the future study of molecular dynamics and advance the measurement of rapid processes that take place in single molecules at the atomic scale.
“A few years ago, I served on a Ph.D. Advancement committee and the graduate student discussed his thesis research involving stochastic processes in nm-scale magnetic tunnel junctions,” Wilson Ho, senior author of the paper, told Phys.org. “The signal in his experiment was affected by the thermal noise and showed a transition when the driving frequency was varied.
Immersing in virtual reality (VR) nature scenes helped relieve symptoms that are often seen in people living with long-term pain, with those who felt more present experiencing the strongest effects.
A new study led by the University of Exeter, published in the journal Pain, tested the impact of immersive 360-degree nature films delivered using VR compared with 2D video images in reducing the experience of pain, finding VR almost twice as effective.
The paper is titled “Immersion in nature through virtual reality attenuates the development and spread of mechanical secondary hyperalgesia: a role for insulo-thalamic effective connectivity.”
A new study offers the first direct evidence that deep-dwelling mesopelagic fish, which account for up to 94% of global fish biomass, excrete carbonate minerals at rates comparable to shallow-water species. The findings validate previous global models suggesting that marine fish are major contributors to biogenic carbonate production in the ocean.
Scientists at the University of Miami Rosenstiel School of Marine, Atmospheric, and Earth Science studied the blackbelly rosefish (Helicolenus dactylopterus), a deep-sea species living at depths of 350–430 meters (1,148–1,410 feet), to determine whether it forms and excretes intestinal carbonate—known as ichthyocarbonate. This physiological process, common among marine fish, helps maintain internal salt and water balance in saline environments and plays a critical role in marine carbon cycling.
The study, titled “Osmoregulation by the gastro-intestinal tract of marine fish at depth—implications for the global carbon cycle,” was published on July 15, 2025 in the Journal of Experimental Biology.
University of Kentucky Markey Cancer Center researchers have discovered a genetic biomarker that could help identify patients with glioblastoma most likely to benefit from the cancer drug bevacizumab.
The study, published in JCO Precision Oncology, found that brain tumors from patients treated with bevacizumab who lived longer were more likely to have a genetic change called CDK4 amplification. This suggests that testing for the molecular marker could help oncologists identify patients most likely to respond well to bevacizumab treatment.
“The findings could help oncologists make more informed treatment decisions for glioblastoma patients, potentially sparing those unlikely to benefit from unnecessary side effects while ensuring those who might respond get access to the drug,” said John Villano, M.D., Ph.D., the study’s lead author and professor in the UK College of Medicine.
The researchers identified three key factors involved in controlling the invasion routes. The gene ANXA1 was linked to invasion along blood vessels while HOPX and RFX4 was associated with diffuse infiltration in the brain. To evaluate the role of the genes, the researchers tested to knock them out in preclinical models, which resulted in a shift in the tumor’s invasion pattern. In several cases, the survival of the experimental animals was also prolonged.
The researchers also discovered proteins encoded by the identified genes in tissue samples from patients. In addition, they found that the presence of the ANXA1 and RFX4 correlated with poor survival. This indicates that these proteins could have a value as prognostic biomarkers.
An international research team has identified new mechanisms behind how the aggressive brain tumor glioblastoma spreads in the brain. Targeting the identified connection between the tumor invasion routes and the tumor cell states could be a potential new treatment strategy.
Glioblastoma is the most common and most lethal primary brain cancer in adults, known for its capacity to spread locally in the brain rather than forming distant metastases. The locally infiltrating cells are largely out of reach for current therapies and it is therefore crucial to determine how the spread in the brain is controlled.
In the current study, which was recently published in the journal Nature Communications, the researchers found that some tumor cells choose to grow along blood vessels in the brain whereas others spread diffusely in the brain tissue. This choice is controlled by the tumor cell states.
The optical crystal can survive extreme temperatures and cosmic radiation, is nigh-impervious to physical impact, resists most chemicals, and can endure for billions of years.
