Lifeboat Foundation: Safeguarding Humanity
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In the largest study of its kind, scientists report how combining health data with whole genome sequence (WGS) data in patients with cancer can help doctors provide more tailored care for their patients.

The research, published in Nature Medicine, shows that linking WGS data to real-world clinical data can identify changes in cancer DNA that may be relevant for an individual patient’s care, for example by helping identify what treatment might work best for them based on their cancer.

The study, led by Genomics England, NHS England, Queen Mary University of London, Guy’s and St Thomas’ NHS Foundation Trust and the University of Westminster, analyzed data covering over 30 types of solid tumors collected from more than 13,000 participants with cancer in the 100,000 Genomes Project. By looking at the alongside routine clinical data collected from participants over a 5-year period, such as hospital visits and the type of treatment they received, scientists were able to find specific genetic changes in the cancer associated with better or worse survival rates and improved patient outcomes.

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Shares of Amazon closed up 1.5% on Wednesday.

Last November, the European Commission warned the planned acquisition raises competition concerns, saying it found Amazon may have the ability to prevent or degrade iRobot rivals’ access to its online site by delisting or reducing the visibility of their products in search results and other areas.

The European Commission opened an in-depth probe into the purchase last July and is expected to rule on the deal by Feb. 14.

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Hummingbirds use two distinct sensory strategies to control their flight, depending on whether they’re hovering or in forward motion, according to new research by University of British Columbia (UBC) zoologists.

“When in forward fight, hummingbirds rely on what we call an ‘internal forward model’—almost an ingrained, intuitive autopilot—to gauge speed,” says Dr. Vikram B. Baliga, lead author of a new study on hummingbird locomotion published in Proceedings of the Royal Society B. “There’s just too much information coming in to rely directly on every from your surroundings.”

“But when hovering or dealing with cues that might require a change in altitude, we found they rely much more on , direct visual feedback from their environment.”

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Rapid-acting antidepressants, including ketamine, scopolamine and psilocybin, have been found to have immediate and lasting positive effects on mood in patients with major depressive disorder but how these effects arise is unknown. New research led by the University of Bristol explored their neuropsychological effects and found that all three of these drugs can modulate affective biases associated with learning and memory.

The paper, published in Science Translational Medicine was carried out in collaboration with researchers at Compass Pathways, Boehringer Ingelheim, and the University of Cambridge.

Negative affective biases are a core feature of . Affective biases occur when emotions alter how the brain processes information and negative affective biases are thought to contribute to the development and continuation of depressed mood.

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Space coiling acoustic metamaterials are static and require manual reconfiguration for sound-field modulation. In a new report published in Communications Materials, Christabel Choi, and a team of scientists in computer science and engineering in the U.K., and Italy, developed an approach for active reconfiguration with standalone dynamics to space-coil unit cells known as dynamic meta-bricks.

The meta-bricks housed an actuatable, magnetorheological, elastomeric flap, to function like a switch and to directly regulate the transmitted ultrasound. The scientists showed the synergy between active and passive reconfigurability to develop multifunctional metamaterials with additional degrees of freedom, for design and implementation.

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Jan 11 (Reuters) — The University of Oxford said on Thursday it had begun human testing of an experimental vaccine against the brain-swelling Nipah virus that led to outbreaks in India’s Kerala state and other parts of Asia.

There is no vaccine yet for the deadly virus. Nipah was first identified about 25 years ago in Malaysia and has led to outbreaks in Bangladesh, India and Singapore.

The first participants in the Oxford trial received doses of the vaccine over the last week. The shot is based on the same technology as the one used in AstraZeneca (AZN.L) and Serum Institute of India’s COVID-19 shots.

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