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Repost, but if you know someone’s dealing with such, the information can help you and them. The suppressing of it can not help anyone.

Alzheimer’s disease varies widely in its age of onset, presentation, and severity. Recently, the SORL1 gene has received increased attention since variations in this gene have been associated with both early-and late-onset Alzheimer’s. However, little is known about how damage to SORL1 leads to disease.

Using stem cells from patients with Alzheimer’s, investigators from Harvard-affiliated Brigham and Women’s Hospital found that loss of normal SORL1 function leads to a reduction in two key proteins known to be involved in Alzheimer’s and which play an essential role in the neurons of healthy individuals.

Their results, published in Cell Reports, suggest a potential strategy for Alzheimer’s disease treatment, especially for patients not responsive to existing therapies.

Continue reading “‘Molecular road’ to Alzheimer’s leads to new treatment strategy” | >

The last 2 questions and the answers are great. The first starts at 30 minutes. And I like his answer to the 2nd question especially, the time is 33:54. “What is giving me great hope is that we’re entering the phases where we have more than enough tools to get really get close to escape velocity.”

Genome Engineering for Healthy Longevity – George Church at Longevity Summit Dublin 2023.

#GeorgeChurch #GenomeEngineering #HealthyLongevity #LongevitySummitDublin2023 #AgingResearch #DublinConference #LongevityScience #BiomedicalEngineering #GeneticModification #DublinTalks #GenomicInnovation #MedicalScience #LongevityResearch #PrecisionMedicine #AgingInterventions #Healthspan #GenomeEditing #AntiAging #LongevityInsights #Genetics #Innovation

Continue reading “Longevity Summit Dublin” | >

The transition to Artificial General Intelligence (AGI) signifies more than a change in terminology; it represents a major leap in capabilities. It will take many years for AGI to be fully realized, but we are well underway in this evolution. In the meantime, most of the AI applications developed remain classified as NarrowAI.

Simply, AGI is any task that a human can do could be accomplished by general AI. It technically has all the potential of a human brain. It could tackle any problem or task in any area, whether it be music composition or logistics—all the potential actions humans can perform.

This article discusses General AI and highlights how the AI industry is unfolding advancing efforts to develop General AI.

Read more | >

You cannot read any newspaper, media report, or publication these days without a mention of AI and its impact to disrupting business in shaping new ways or working, augmenting human intelligence, or raising genuine fears of what have we unleashed in our societal structures.

IBM’s survey in 2022 predicted that the AI global adoption is already over 35 percent in using AI to modernize business practices and processes.

It’s already over a decade now since Oxford researchers, Carl Frey and Michael Osborne in their seminal research, declared that over 47 percent of jobs would disappear by 2030.

Even futurists like Kevin Kelly were warning back in 2016 that the Robots are Coming.

What is the… More.

Continue reading “Is AI Threatening Our Jobs?” | >

The Federal Court of Appeal in the USA has just ruled that Google is not covered by exemption for journalistic or artistic work.in a 2–1 court ruling, Google which drives more than 75% of internet searches in Canada, which opens the door for people to demand that their names in any articles are made unsearchable known as the right to be forgotten.

Valerie Lawton, a spokeswoman for the Office of the Canadian Privacy Commissioner, said it is pleased the court agreed with its position that Google’s search engine service is subject to federal privacy law. “This brings welcome clarification to this area of the law.”

This legal case was actually started in 2017 when a complaint to the Federal… More.

This article discusses the recent ruling that opens the door to the right to be forgotten challenging Google and supporting Privacy Legislation protect our privacy.

Continue reading “Google Faced With An AI Privacy Challenge: Do I Have The Right To Be Forgotten?” | >

Educators just started recovering from the profound impact of the COVID-19 pandemic. Some studies assess that the learning loss may never be recovered. However, a new challenge has crashed on the shores of education — AI — which could be even more impactful. In this post, we look at the challenges that AI brings to education, some ideas, and steps being taken.

A look at the newly announced Generative AI guidance from UNESCO, and others. An explanation of what they mean for application.

Read more | >

Some people come to therapy feeling overwhelmed and uncertain about their tendency to pick up and put down hobbies on a whim. They ask questions like:“Why do I feel so scattered, hopping from one interest to another?”

“Is it normal to want to learn so many things, or am I just avoiding commitment?”“Why do I feel like I’m not truly excelling in any one area despite my many pursuits?”

The pervasive cultural narrative has often celebrated specialization, making those with multifaceted interests feel out of place. Society has long valued depth over breadth, equating mastery in a single field with success and purpose. This has led to a collective anxiety: the fear of missing out on becoming an… More.

While we once frowned upon the “jack of all trades,” an array of hobbies might reveal a quest for a psychologically rich life—one that fosters depth, curiosity and growth.

Continue reading “There’s No Such Thing As Too Many Hobbies—A Psychologist Explains” | >

The explosive recent growth of AI tools to generate text, images, or audio relies on gargantuan amounts of information.

That information doesn’t come for free. It can exact high – and unequal – costs in terms of energy, water, and labor, though these costs are largely invisible to users.

In terms of energy, generative AI models typically depend on extremely large-scale cloud providers, which use chips with more transistors that require at least 10 times as much energy as traditional versions. Unsurprisingly, models that use more training data and contain more parameters tend to guzzle more energy.

Read more | >

The 2 SOPS or 2nd Space Operations Squadron commander, Lt Col Robert Wray… More.

Of all the missions the Space Force performs daily for a grateful nation, there is none more ubiquitous and essential than GPS. Today’s soldiers and sailors depend on reliable, accurate, and secure GPS as much as they do any weapon they employ. Meanwhile, the rest of the world is just as dependent on GPS to enable basic mobility and underpins every other sector of the modern global economy. The criticality of secure global navigation and timing to both warfighting and the national economy makes it unique – we simply could not go a day without space. In so few words, GPS’ future is ground zero for the new space race.

The 2 SOPS or 2nd Space Operations Squadron commander, Lt Col Robert Wray reminds me that “14 of the 16 critical infrastructures designated by the Department of Homeland Security rely on 24/7 GPS to operate for the country.” But the newest GPS satellites in use today are the same school bus sized ones Gen. Hyten has lamented are, “juicy targets” for our adversaries – marvels of modern engineering, yes, but no longer sufficient to meet modern needs.

Alternatives to GPS, categorically called Global Navigation Satellite Systems (GNSS), are growing rapidly because the old GPS system we rely on offers neither the precision nor security needed in an increasingly autonomous, rule based, and precisely timed world. What exactly needs to change then, aside from smaller, faster satellites as technology becomes more efficient and readily available? There are major challenges with the current system that today’s Guardians are already working on. But to usher in a new and improved GPS capability, the government needs to adopt artificial intelligence and machine learning to enhance squadron operations, work to better integrate commercial software into current GPS constellation to get the most out of current capabilities, and continue to invest in the next generation of leaders. Private capital has begun aligning with companies aiming to solve these future deficiencies, in a race against pacing threats like China and Russia.

Continue reading “A Day Without Space: GPS Is Ground Zero For The New Space Race” | >

Indirect observations of a strange isotope of nitrogen, nitrogen-9, could open new avenues of understanding of nuclear theory.

A group of researchers has discovered direct evidence of a new atomic nucleus that stretches what we understand of nuclear physics. Called nitrogen-9, this isotope contains seven protons and two neutrons and only exists for one billionth of a nanosecond. That is such a minute amount of time that it is difficult for scientists to agree if this really is an atomic isotope or not.

EzumeImages/iStock.

“Totally new physics”

Continue reading “New nitrogen isotope stretches our understanding of nuclear physics” | >