Lifeboat Foundation: Safeguarding Humanity
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Diets that are higher in fat and significantly lower in carbohydrates are known to have a drastic effect on reducing the incidence of seizures in individuals with drug-resistant forms of epilepsy, particularly among children.

While it’s becoming apparent the diet creates some sort of shift in the gut’s microflora, the precise nature of those changes and their connection to the prevalence of seizures remains a mystery.

In a prospective study on children and experiments involving mice, researchers from the University of California, Los Angeles (UCLA) bring us a step closer to understanding how the foods we eat alter the functions of microbes in our digestive system, which in turn affect a variety of neurological functions suspected to play a role in epilepsy.

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Researchers are actively engaged in the dynamic manipulation of quantum systems and materials to realize significant energy management and conservation breakthroughs.

This endeavor has catalyzed the development of a cutting-edge platform dedicated to creating quantum thermal machines, thereby unlocking the full potential of quantum technologies in advanced energy solutions.

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A team of researchers has analyzed more than one million galaxies to explore the origin of the present-day cosmic structures, reports a recent study published in Physical Review D as an Editors’ Suggestion.

Until today, precise observations and analyses of the cosmic microwave background (CMB) and large-scale structure (LSS) have led to the establishment of the standard framework of the universe, the so-called ΛCDM model, where cold dark matter (CDM) and dark energy (the cosmological constant, Λ) are significant characteristics.

This model suggests that primordial fluctuations were generated at the beginning of the universe, or in the early universe, which acted as triggers, leading to the creation of all things in the universe including stars, galaxies, galaxy clusters, and their spatial distribution throughout space. Although they are very small when generated, fluctuations grow with time due to the gravitational pulling force, eventually forming a dense region of dark matter, or a halo. Then, different halos repeatedly collided and merged with one another, leading to the formation of celestial objects such as galaxies.

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Just as healthy organs are vital to our well-being, healthy organelles are vital to the proper functioning of the cell. These subcellular structures carry out specific jobs within the cell; for example, mitochondria power the cell, and lysosomes keep the cell tidy.

Although damage to these two organelles has been linked to aging, cellular senescence, and many diseases, the regulation and maintenance of these organelles have remained poorly understood. Now, researchers at Osaka University have identified a protein, HKDC1, that plays a key role in maintaining these two organelles, thereby acting to prevent cellular aging.

There was evidence that a protein called TFEB is involved in maintaining the function of both organelles, but no targets of this protein were known. By comparing all the genes of the cell that are active under particular conditions and by using a method called , which can identify the DNA targets of proteins, the team was the first to show that the gene encoding HKDC1 is a direct target of TFEB, and that HKDC1 becomes upregulated under conditions of mitochondrial or lysosomal stress.

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In a public lecture titled “The Meaning of Spacetime,” renowned physicist Juan Maldacena outlined ideas that arose from the study of quantum aspects of black holes.

V/ Perimeter Institute

On July 27, Juan Maldacena, a luminary in the worlds of string theory and quantum gravity, will share his insights on black holes, wormholes, and quantum entanglement.

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