Voltage imaging enables scientists to visualize neural activity using voltage-sensitive fluorescent sensors. What do you need for voltage imaging?
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For centuries, scientists have grappled with the most fundamental question of them all — what is reality?Is it a matter of common sense? Or can God or some h…
The phrase “MRI for AI” rolls off the tongue with the seductive clarity of a metaphor that feels inevitable. Dario Amodei, CEO of Anthropic, describes the goal in precisely those terms, envisioning “the analogue of a highly precise and accurate MRI that would fully reveal the inner workings of an AI model” (Amodei, 2025, para. 6). The promise is epistemic X‑ray vision — peek inside the black box, label its cogs, excise its vices, certify its virtues.
Yet the metaphor is misguided not because the engineering is hard (it surely is) but because it mistakes what cognition is. An artificial mind, like a biological one, is not a spatial object whose secret can be exposed slice by slice. It is a dynamical pattern of distinctions sustained across time: self‑referential, operationally closed, and constitutionally allergic to purely third‑person capture. Attempting to exhaust that pattern with an interpretability scanner is as quixotic as hoping an fMRI might one day disclose why Kierkegaard chooses faith over reason in a single axial slice of BOLD contrast.
Phenomenology has warned us for more than a century that interiority is not an in‑there to be photographed but an ongoing enactment of world‑directed sense‑making. Husserl’s insight that “consciousness is always consciousness of something” (Ideas I, 1913) irreversibly welds experience to the horizon that occasions it; any observation from the outside forfeits the very structure it hopes to catch.
These are your rudimentary seed packages… Some will combine in place to form more complicated structures.’ — Greg Bear, 2015.
Robot Bricklayer Or Passer-By Bricklayer? ‘Oscar picked up a trowel. ‘I’m the tool for the mortar,’ the little trowel squeaked cheerfully.’ — Bruce Sterling, 1998.
Organic Non-Planar 3D Printing ‘It makes drawings in the air following drawings…’ — Murray Leinster, 1945.
Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.
The new report, published in The American Journal of Clinical Nutrition, is based on data from a VITAL sub-study co-led by researchers at Mass General Brigham and the Medical College of Georgia, and supports a promising role in slowing a pathway for biological aging.
“VITAL is the first large-scale and long-term randomized trial to show that vitamin D supplements protect telomeres and preserve telomere length,” said co-author JoAnn Manson, MD, principal investigator of VITAL and chief of the Division of Preventive Medicine at Brigham and Women’s Hospital.
Anthropic’s Claude Opus 4 outperforms OpenAI’s GPT-4.1 with unprecedented seven-hour autonomous coding sessions and record-breaking 72.5% SWE-bench score, transforming AI from quick-response tool to day-long collaborator.
New research suggests vitamin D may help slow biological aging by preserving telomere length.
The COVID-19 pandemic increased public awareness of the importance of mask use for personal protection. However, when the mesh size of mask fabrics is small enough to capture viruses, which are usually around one hundred nanometers in size, the fabric typically also restricts air flow, resulting in user discomfort. Researchers from Japan have now developed a new filter material that effectively captures nanoparticles, although further improvements are needed to make it suitable for comfortable mask use.
In a study published this month in Materials Advances, researchers from the Institute of Industrial Science at the University of Tokyo have developed a filter capable of capturing nanoparticles such as viruses. While the filter demonstrates high filtration efficiency, its airflow resistance is currently higher than the standards required for face masks, indicating that additional development is necessary before it can be used for personal protective equipment.
The filter is constructed from nanosheets consisting of an ordered mesh composed of porphyrins, which are flat, ring-shaped molecules with a central hole. The tiny holes in the porphyrin molecules are suitably sized to allow the easy passage of the small gas molecules in air while blocking the movement of larger particles, such as viruses. The nanosheets are then supported on a fabric modified with nanofibers containing pores of several hundred nanometers to form the filter.