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SpaceX is making significant progress in the development and testing of the Starship, with the completion of roof and wall structures, installation of cryo pipe insulation, and advanced development of the booster in the Rocket Garden.

Questions to inspire discussion.

What progress has SpaceX made with the Starship?
—SpaceX has completed roof and wall structures, installed cryo pipe insulation, and advanced development of the booster in the Rocket Garden.

Mini brains grown in a lab from stem cells spontaneously developed rudimentary eye structures, scientists reported in a fascinating paper in 2021.

On tiny, human-derived brain organoids grown in dishes, two bilaterally symmetrical optic cups were seen to grow, mirroring the development of eye structures in human embryos.

This incredible result will help us to better understand the process of eye differentiation and development, as well as eye diseases.

A team of chemists, microbiologists and physicists at the University of Cambridge in the U.K. has developed a way to use solid-state nanopores and multiplexed DNA barcoding to identify misfolded proteins such as those involved in neurodegenerative disorders in blood samples. In their study, reported in the Journal of the American Chemical Society, the group used multiplexed DNA barcoding techniques to overcome problems with nanopore filtering techniques for isolating harmful oligomers.

Prior research has shown that the presence of harmful oligomers in the brain can lead to misfolding of proteins associated with neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. Medical researchers have been looking for a way to detect them in the blood as a way to diagnose neurodegenerative disease and to track the progression once it has been confirmed.

Unfortunately, finding them in complex mixtures such as blood has proven to be a daunting task. One approach has shown promise—using sensors—but to date, they cannot track target oligomers as they speed through customizable solid-state nanopore sensors. In this new effort, the research team overcame this problem by using customizable DNA nanostructures.

Sandy talks Cybertruck with 5 Tesla Execs! Lars Moravy: Head of Vehicle Engineering Franz von Holzhausen: Head of Design Drew Baglino: Head of Powertrain (battery + motors) and Energy Pete Bannon: Head of Low Voltage David Lau: Head of Software Munro Live is a YouTube channel that features Sandy Munro and other engineers from Munro & Associates.

The prevailing scientific paradigm is that matter is primary and everything, including consciousness can be derived from the laws governing matter. Although the scientific explanation of consciousness on these lines has not been realized, in this view it is only a matter of time before consciousness will be explained through neurobiological activity in the brain, and nothing else. There is an alternative view that holds that it is fundamentally impossible to explain how subjectivity can arise solely out of material processes-“the hard problem of consciousness”-and instead consciousness should be regarded in itself as a primary force in nature. This view attempts to derive, for example, the laws of physics from models of consciousness, instead of the other way around. While as scientists we can understand and have an intuition for the first paradigm, it is very difficult to understand what “consciousness is primary” might mean since it has no intuitive scientific grounding. Here we show that worlds experienced through virtual reality (VR) are such that consciousness is a first order phenomenon. We discuss the Interface Theory of Perception which claims that in physical reality perceptions are not veridical and that we do not see the “truth” but that perception is based on evolutionary payoffs. We show that this theory may provide an accurate description of perception and consciousness within VR, and we put forward an experimental study that could throw light on this. We conclude that VR does offer an experimental frame that provides intuition with respect to the idea that “consciousness is first” and what this might mean regarding the perceived world. However, we do not draw any conclusions about the veracity of this notion with respect to physical reality or question the emergence of consciousness from brain function.

Keywords: consciousness; interface theory of perception; perception; presence; real vs. virtual; virtual reality.

Copyright © 2022 Slater and Sanchez-Vives.