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Cutting-edge research engineers skin bacteria to treat acne, presenting a novel therapeutic approach for skin conditions.

In a study led by the Translational Synthetic Biology Laboratory Department of Medicine and Life Sciences (MELIS) at Pompeu Fabra University, an international research team has successfully engineered Cutibacterium acnes, a type of skin bacterium, to secrete a therapeutic molecule to treat acne symptoms. This innovative approach holds promise for addressing skin alterations and other diseases using living therapeutics.

Engineering smart skin bacteria

The study reveals that the researchers have edited the genome of Cutibacterium acnes to produce the NGAL protein, a mediator of the acne drug isotretinoin. This protein has been proven to reduce sebum production by inducing the death of sebocytes, the skin cells responsible for sebum secretion.

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Mathpresso, the creator of QANDA — Asia’s most extensive AI-driven learning platform — has announced that their large language model called MathGPT has achieved a new world record in math, beating OpenAI and Microsoft models.

MathGPT reportedly is now ranked no. 1 in benchmarks that evaluate mathematical ability such as ‘MATH’ (12,500 difficult math problems) and ‘GSM8K’ (8,500 elementary school math problems), beating Microsoft’s ‘ToRA 13B’, the model that held the previous record.

In the MATH benchmark, MathGPT surpassed the performance of OpenAI’s GPT-4.

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HIVE begins testing in deep space.

• Los microrobots de la misión de la UNAM encendieron correctamente, informó Gustavo Medina Tanco • La misión tiene un nivel de éxito mayor al 50 por ciento y se espera que en las próximas horas-y durante la madrugada-se efectúen pruebas que puedan llevar a un 75 por ciento de éxito.

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U.S. Defense and State Department officials aim to meet with delegates from at least 50 other nations by mid-2024 to discuss the nascent framework and standards doctrine they’ve recently signed onto, pledging to “responsibly” develop and deploy artificial intelligence and autonomous military technologies, according to a top Pentagon policymaker.

Originally produced in early 2023, State spotlighted the Political Declaration on Responsible Military Use of AI and Autonomy in November — and confirmed then that more than 40 countries formally endorsed it.

“We’re up to 51 now, including the United States, and we’re proud of the fact that it’s not just the usual suspects,” Michael Horowitz, deputy assistant secretary of defense for force development and emerging capabilities, said on Tuesday during a webcast hosted by the Center for Strategic and International Studies.

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