Lifeboat Foundation

Forget the cloud. Northwestern University engineers have developed a new nanoelectronic device that can perform accurate machine-learning classification tasks in the most energy-efficient manner yet. Using 100-fold less energy than current technologies, the device can crunch large amounts of data and perform artificial intelligence (AI) tasks in real time without beaming data to the cloud for analysis.

With its tiny footprint, ultra-low power consumption and lack of lag time to receive analyses, the device is ideal for direct incorporation into wearable electronics (like smart watches and fitness trackers) for real-time data processing and near-instant diagnostics.

To test the concept, engineers used the device to classify large amounts of information from publicly available electrocardiogram (ECG) datasets. Not only could the device efficiently and correctly identify an irregular heartbeat, it also was able to determine the arrhythmia subtype from among six different categories with near 95% accuracy.

As long as you’ve opted-in to Google SGE, the search bar will double as a generative AI image prompt.

WASHINGTON, Oct 11 (Reuters) — Internet companies Google, Amazon and Cloudflare say they have weathered the internet’s largest-known denial of service attack and are sounding the alarm over a new technique they warn could easily cause widespread disruption.

Alphabet Inc-owned Google (GOOGL.O)said in a blog post published Tuesday that its cloud services had parried an avalanche of rogue traffic more than seven times the size of the previous record-breaking attack thwarted last year.

Internet protection company Cloudflare Inc (NET.N)said the attack was “three times larger than any previous attack we’ve observed.” Amazon.com Inc’s (AMZN.O) web services division also confirmed being hit by “a new type of distributed denial of service (DDoS) event.”

SpaceX’s Starlink satellite internet service has landed a new client in Maersk, as the two companies came to terms on a deal that would provide the company’s Ocean fleet with internet access.

Maersk announced this morning that more than 330 own-operated container vessels will now have Starlink installed, enabling the fleet to access high-speed internet with speeds at over 200 Mbps.

The logistics company said the deal with SpaceX’s Starlink service “is a leap forward in terms of internet speed and latency, which will bring significant benefits in terms of both crew welfare and business impact.”

Chip designer Tachyum has accepted a major purchase order from a U.S. company to build a new supercomputing system for AI. This will be based on its 5 nanometre (nm) “Prodigy” Universal Processor chip, delivering more than 50 exaFLOPS of performance.

Tachyum, founded in 2016 and headquartered in Santa Clara, California, claims to have developed a disruptive, ultra-low-power processor architecture that could revolutionise data centre, AI, and high-performance computing (HPC) markets.

Working with non-human primates, scientists have discovered that the protein SIRT2, a member of the sirtuin family, might play an important role in slowing cardiac aging [1].

In this study published in Nature Aging, the researchers used long-tailed macaques to elucidate the molecular aspects of cardiac aging using multi-omics analysis. Unlike short-lived mice and rats, non-human primates like these have hearts that closely resemble those of humans and, due to their relatively long lifespan, suffer from spontaneous heart conditions as well.

SpaceX’s Starlink will be available on most aircraft soon, said Elon Musk. The technology will be available for use by any operator if it is ordered.

Some operators provide an internet connection during airplane flights. However, if you try to use it, you will most likely encounter a problem. The problem with most in-flight internet offerings is speed and connectivity. Airplanes connected to the antenna receive signals from communications towers on the ground as they fly overhead. This limits the availability of internet: it becomes unstable, difficult to connect to, and the actual speed reaches no more than about 10 Mbps. That is why satellite internet can offer a number of benefits, and SpaceX’s Starlink will soon do just that.

Currently, Starlink has a constellation of about 5,000 satellites in low Earth orbit and plans to increase this to 42,000 in the future. This is significantly more than all other companies combined. For example, Viasat, which provides in-flight internet service to JetBlue, United Airlines, and American Airlines, operates a fleet of four satellites, according to The Street.

Controlling the adipo-osteogenic lineage commitment of bone marrow mesenchymal stem cell (BMSC) in favor of osteogenesis is considered a promising approach for bone regeneration and repair. Accumulating evidence indicates that oxidative phosphorylation (OXPHOS) is involved in regulating cell fate decisions. As an essential cofactor for OXPHOS, nicotinamide adenine dinucleotide (NAD) has been shown to correlate with the differentiation of stem cells. However, whether NAD manipulates BMSC lineage commitment through OXPHOS remains elusive. Therefore, it is critical to investigate the potential role of NAD on energy metabolism in mediating BMSC lineage commitment.

In this study, the mitochondrial respiration and intracellular NAD⁺ level were firstly compared between osteogenic and adipogenic cells. For validating the role of NAD in mitochondrial OXPHOS, the inhibitor of NAD⁺ salvage pathway FK866 and activator P7C3 were used to manipulate the NAD⁺ level during osteogenesis. Furthermore, a murine femur fracture model was established to evaluate the effect of FK866 on bone fracture repair.

We elucidated that osteogenic committed BMSCs exhibited increased OXPHOS activity and a decreased glycolysis accompanied by an elevated intracellular NAD⁺ level. In contrast, adipogenic committed BMSCs showed little change in OXPHOS but an upregulated activity in glycolysis and a decline in intracellular NAD⁺ level in vitro. Moreover, attenuates of NAD⁺ via salvage pathway in BMSCs diminished osteogenic commitment due to mitochondria dysfunction and reduced activity of OXPHOS. The cells were rescued by supplementing with nicotinamide mononucleotide. In addition, treatment with NAD⁺ inhibitor FK866 impaired bone fracture healing in vivo.

Ceramic nanowires could essentially be used even for car tires reducing even hazardous rubber waste.

A team of MIT-led engineers found a simple, inexpensive way to strengthen Inconel 718 with ceramic nanowires to be used in metal PBF AM processes. The team believes that their general approach could be used to improve many other materials. “There is always a significant need for the development of more capable materials for extreme environments. We believe that this method has great potential for other materials in the future,” said Ju Li, the Battelle Energy Alliance Professor in Nuclear Engineering and a professor in MIT’s Department of Materials Science and Engineering (DMSE).

Li, who is also affiliated with the Materials Research Laboratory (MRL), is one of three corresponding authors of a paper on the work that appeared in the April 5 issue of Additive Manufacturing. The other corresponding authors are Professor Wen Chen of the University of Massachusetts at Amherst and Professor A. John Hart of the MIT Department of Mechanical Engineering.

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