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We’ve all heard the claim: atoms are mostly empty space. That if you zoomed in far enough, you’d find 99.9999999999999% of an atom is just… nothing. But this idea, while popular, is deeply misleading.

In this video, we dive into the quantum reality behind that empty space — and reveal what truly fills the “void” inside atoms. From the discovery of the nucleus to the rise of quantum field theory, we’ll explore how jittering fields, zero-point energy, and vacuum fluctuations reshape our understanding of what “nothing” really is.

Along the way, you’ll learn:

Why Rutherford’s model gave birth to the “empty atom” idea.

Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using CRISPR-Cas9 in combination with AAV6 vectors can trigger inflammatory and senescence-like responses in blood stem cells, compromising their long-term ability to regenerate the blood system.

The study, published in Cell Reports Medicine, outlines new strategies to overcome this hurdle, improving both the safety and efficacy of -based therapies for inherited blood disorders.

The research was led by Dr. Raffaella Di Micco, group leader at SR-Tiget, New York Stem Cell Foundation Robertson Investigator and Associate Professor at the School for Advanced Studies (IUSS) of Pavia, in collaboration with Professor Luigi Naldini, Director of SR-Tiget, and several European research partners.

Fibroblasts are specialised connective tissue cells that play a key role in wound healing and tissue regeneration. The recent scientific publication from the University of Leipzig Medical Center shows that fibroblasts respond differently depending on the organ and disease context. Their functions are shaped by their embryonic origin, tissue-specific signals, and pathological stimuli. These specialised cells are not only involved in tissue repair and remodelling, but also influence the immune system and the development of diseases such as cancer, fibrosis and chronic inflammatory conditions.

“Until now, our understanding of fibroblast diversity has been based primarily on studies in animal models. This new review is the first to compare and integrate extensive human studies that have used modern single-cell technologies. This approach makes it possible to combine findings from different human studies, creating a comprehensive picture of the various origins and functions of human fibroblasts,” says Professor Sandra Franz, lead author of the study from the University of Leipzig Medical Center.

This deeper understanding of cellular heterogeneity opens up new avenues for the development of targeted therapies.

Astronomers have filled a large gap in knowledge about Mars’ water cycle. Their research on water percolating from surface to aquifer could change the picture of what early Mars was like, suggesting that less of the planet’s water may have been available to become rain and refill lakes and oceans.

Billions of years ago, water flowed on the surface of Mars. But scientists have an incomplete picture of how the Red Planet’s water cycle worked.

That could soon change after two graduate students at The University of Texas at Austin filled a large gap in knowledge about Mars’ water cycle — specifically, the part between surface water and groundwater.

What if accessing knowledge, which used to require hours of analyzing handwritten scrolls or books, could be done in mere moments?

Throughout history, the way humans acquire knowledge has experienced great revolutions. The birth of writing and books altered learning, allowing ideas to be preserved and shared across generations. Then came the Internet, connecting billions of people to vast information at their fingertips.

Today, we stand at another shift: the age of AI tools, where AI doesn’t just give us answers—it provides reliable, tailored responses in seconds. We no longer need to gather and evaluate the correct information for our problems. If knowledge is now a tool everyone can hold, the real revolution starts when we use this superpower to solve problems and improve the world.

New YT video, featuring RAADFest creator, James Strole!


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