Researchers at Karolinska Institutet, in collaboration with teams from Lund University and the Center for Regenerative Therapies Dresden (CRTD), have mapped the genome of the Iberian ribbed newt and revealed how the composition and organization of the DNA are linked to its ability to regenerate entire body parts.
The paper is published in the journal Cell Genomics.
Salamanders are known for their unique ability to regenerate entire body parts and for their resistance to tumor development. The molecular mechanisms behind these traits have been difficult to study due to a lack of knowledge about the composition of their genome. Researchers at Karolinska Institutet have now succeeded in mapping the genome of the Iberian ribbed newt, providing new insights into these fascinating processes.