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How Obesity Dismantles the Powerhouse of the Cell: A new UC San Diego School of Medicine study in Nature Portfolio (Metabolism) sheds light on how obesity affects our mitochondria, the all-important energy-producing structures of our cells.


UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.

TikTok built its empire off popular music — but now it’s losing access to a ton of it.

In a statement, Universal Music Group said it has chosen to “call time out on TikTok” to pressure the social network for better rules on artificial intelligence, online safety, and artist compensation for its roster, which includes such luminaries as Taylor Swift, Drake, and BTS.

“Today, as an indication of how little TikTok compensates artists and songwriters, despite its massive and growing user base, rapidly rising advertising revenue and increasing reliance on music-based content, TikTok accounts for only about 1 percent of our total revenue,” the statement reads.

A consensus has arisen in the astronomical community that familiar matter made of atoms is not the dominant form of matter in the Universe. Instead, an invisible form of matter, called dark matter, is thought to be far more prevalent. However, a small group of researchers deny the existence of dark matter, instead saying our understanding of how objects move is incomplete. A recent paper in the Monthly Notices of the Royal Astronomical Society seems to have ruled this out definitively.

Stars, planets, and galaxies move under the direction of the force of gravity, and Isaac Newton worked out the laws that govern that motion, which we now call Newtonian dynamics. However, despite the enormous success of Newtonian dynamics, this success is not universal. Indeed, when Newton’s equations are applied to certain astronomical phenomena, they do not make the correct predictions. One such example is the speed at which galaxies rotate. When astronomers measure the speed of stars in the periphery of a galaxy, they move faster than can be explained by accepted theory. Instead, the galaxies should fly apart.

The solution to this mystery favored by most scientists is that beyond the familiar stars and clouds of gas, our galaxy also hosts a large amount of invisible matter, called dark matter. This dark matter adds to the gravitational force holding the galaxy together. Thus, the evidence for dark matter is indirect. It has never been observed in the laboratory; yet its ability to explain the motion of galaxies is strong circumstantial evidence that it exists.

Metalenses have been used to image microscopic features of tissue and resolve details smaller than a wavelength of light. Now they are going bigger.

Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a 10-centimeter-diameter glass metalens that can image the sun, the moon and distant nebulae with high resolution.

It is the first all-glass, large-scale metalens in the visible wavelength that can be mass produced using conventional CMOS fabrication technology.

In the world of quantum computing, the spotlight often lands on the hardware: qubits, superconducting circuits, and the like. But it’s time to shift our focus to the unsung hero of this tale – the quantum software, the silent maestro orchestrating the symphony of qubits. From turning abstract quantum algorithms into executable code to optimizing circuit designs, quantum software plays a pivotal role.

Here, we’ll explore the foundations of quantum programming, draw comparisons to classical computing, delve into the role of quantum languages, and forecast the transformational impact of this nascent technology. Welcome to a beginner’s guide to quantum software – a journey to the heart of quantum computing.

Quantum vs. Classical Programming: The Core Differences.