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Posted in cosmology, information science, quantum physics, robotics/AI | Leave a Comment on Quantum AI chip taps into “parallel universes” and solves equation in 5 minutes that would normally take 1 septillion years
Google’s Willow chip achieves scalable quantum error correction, reducing errors, and maintaining stability across a million cycles.
Scientists have discovered a key protein that helps cancer cells avoid detection by the immune system during a type of advanced therapy.
By creating a new drug that blocks this protein, researchers hope to make cancer treatments more effective, especially for hard-to-treat blood cancers. This breakthrough could lead to better survival rates and fewer relapses for patients.
Scientists at City of Hope, one of the leading cancer research and treatment centers in the U.S., have uncovered a key factor that allows cancer cells to evade CAR T cell therapy.
OpenAI is giving users a new way to talk to its viral chatbot: 1–800-CHATGPT.
By dialing the U.S. number (1−800−242−8478) or messaging it via WhatsApp, users can access an “easy, convenient, and low-cost way to try it out through familiar channels,” OpenAI said Wednesday. At first, the company said callers will get 15 minutes free per month.
The news follows a barrage of updates from OpenAI as part of a 12-day release event. The most notable announcement was the official rollout of Sora, OpenAI’s buzzy AI video-generation tool.
Researchers at the University of Hawai’i at Mānoa have discovered that a virus, FloV-SA2, encodes one of the proteins needed to make ribosomes, the central engines in all cells that translate genetic information into proteins, the building blocks of life. This is the first eukaryotic virus (a virus that infects eukaryotes, such as plants, animals, fungi) found to encode such a protein.
The research is published in the journal npj Viruses.
Viruses are packets of genetic material surrounded by a protein coating. They replicate by getting inside of a cell where they take over the cell’s replication machinery and direct it to make more viruses. Simple viruses depend almost exclusively on material and machinery provided by the host cell, but larger, more complex viruses code for numerous proteins to aid in their own replication.
Exploring the potential of glycomimetic peptides as powerful anti-inflammatory therapeutic treatments.
As the amount of genomic data grows, so too does the challenge of organizing it into a usable database. Indeed, the lack of a searchable database of genomic information from the literature has posed a challenge to the research community. Now, Genomenon’s AI-based approach—the Genomenon Genomic Graph (G3) knowledgebase—combines patient and biological data from nearly all published scientific and medical studies, including demographics, clinical characteristics, phenotypes, treatments, outcomes, and disease-associated genes and variants.
Training of the underlying large language model for G3 uses Genomenon’s proprietary, curated genomic datasets. The knowledgebase will power AI-driven predictive models for clinical diagnostics and drug development applications.
The Ann Arbor, MI, based Genomenon—a provider of genomic intelligence solutions—notes that this advancement represents the first time that content from the entire corpus of clinically relevant literature will be captured in a single, searchable knowledgebase.
An international research team has used the James Webb Space Telescope (JWST) to observe massive galaxies discovered by the Subaru Telescope in a corner of the early universe known as the Spiderweb protocluster. The JWST results confirm what had been suggested from the Subaru Telescope observations, namely that supermassive black hole activity can truncate the growth of galaxies.
These results appear in the paper “Spider-Webb: JWST Near Infrared Camera resolved galaxy star formation and nuclear activities in the Spiderweb protocluster at z=2.16” in Monthly Notices of the Royal Astronomical Society on December 18, 2024.
The growth and evolution of galaxies is a major theme in modern astronomy. The origin of giant elliptical galaxies is one riddle. These galaxies consist entirely of old stars, so something early in their evolution must have shut off star formation in the progenitors of giant elliptical galaxies. According to one theory, the supermassive black holes at the hearts of the galaxies may play a role in determining the star formation.
📝 — Sheikh, et al.
In this paper, the authors summarize the current practice and the latest progress of CD19 auto-CAR T cell therapy and the management of specific toxicities and discuss the place of allogeneic CAR T development in this setting.
Full text is available 👇
While more than half of non-Hodgkin lymphomas (NHL) can be cured with modern frontline chemoimmunotherapy regimens, outcomes of relapsed and/or refractory (r/r) disease in subsequent lines remain poor, particularly if considered ineligible for hematopoietic stem cell transplantation. Hence, r/r NHLs represent a population with a high unmet medical need. This therapeutic gap has been partially filled by adoptive immunotherapy. CD19-directed autologous chimeric antigen receptor (auto-CAR) T cells have been transformative in the treatment of patients with r/r B cell malignancies. Remarkable response rates and prolonged remissions have been achieved in this setting, leading to regulatory approval from the U.S. Food and Drug Administration (FDA) of four CAR T cell products between 2017 and 2021.
