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Feb 6, 2022

New Research Finds That With Obesity, the Problem Isnโ€™t an Excess of Fat but Its Loss of Function

Posted by in categories: biotech/medical, life extension

What exactly is Obesity?


Obesity is known to cause cardiometabolic diseases like hypertension and diabetes but attributing these diseases to merely an overabundance of fat is a simplification. On a basic level, fat acts as a receptacle to store energy, but upon a closer look it is an essential actor in vital bodily processes like the immune response, the regulation of insulin sensitivity, and maintenance of body temperature. In a review published in the journal Cell on February 3rd, 2022, researchers argue that the negative health effects of obesity stem not simply from an excess of fat but from the decline in its ability to respond to changes, or in other words, its plasticity.

The makeup and functioning of this tissue changes in response to weight fluctuations and aging. As fat declines in plasticity due to aging and obesity, it loses its ability to respond to bodily cues. In the current model of this phenomenon, the rapid growth of adipose tissue outpaces its blood supply, depriving the fat cells of oxygen and causing the accumulation of cells that no longer divide. This leads to insulin resistance, inflammation, and cell death accompanied by the uncontrolled spill of lipids from these cells.

Continue reading “New Research Finds That With Obesity, the Problem Isnโ€™t an Excess of Fat but Its Loss of Function” »

Feb 2, 2022

Kids Can Infer Close Relationships Through Saliva Sharing

Posted by in category: futurism

๐˜ฝ๐™ช๐™ฉ ๐™๐™ค๐™ฌ ๐™™๐™ค ๐™ฎ๐™ค๐™ช๐™ฃ๐™œ ๐™˜๐™๐™ž๐™ก๐™™๐™ง๐™š๐™ฃ ๐™œ๐™ง๐™ค๐™ฌ ๐™ฉ๐™ค ๐™ช๐™ฃ๐™™๐™š๐™ง๐™จ๐™ฉ๐™–๐™ฃ๐™™ ๐™ฉ๐™๐™š๐™จ๐™š ๐™ง๐™š๐™ก๐™–๐™ฉ๐™ž๐™ซ๐™š๐™ก๐™ฎ ๐™˜๐™ค๐™ข๐™ฅ๐™ก๐™š๐™ญ ๐™จ๐™ค๐™˜๐™ž๐™–๐™ก ๐™–๐™ง๐™ง๐™–๐™ฃ๐™œ๐™š๐™ข๐™š๐™ฃ๐™ฉ๐™จ ๐™–๐™ฃ๐™™ ๐™ช๐™จ๐™š ๐™ฉ๐™๐™š๐™ข ๐™ฉ๐™ค ๐™ฃ๐™–๐™ซ๐™ž๐™œ๐™–๐™ฉ๐™š ๐™ฉ๐™๐™š ๐™ฌ๐™ค๐™ง๐™ก๐™™? ๐™๐™š๐™จ๐™š๐™–โ€ฆ See more.

The Neuro-Network.

๐Š๐ข๐๐ฌ ๐‚๐š๐ง ๐ˆ๐ง๐Ÿ๐ž๐ซ ๐‚๐ฅ๐จ๐ฌ๐ž ๐‘๐ž๐ฅ๐š๐ญ๐ข๐จ๐ง๐ฌ๐ก๐ข๐ฉ๐ฌ ๐“๐ก๐ซ๐จ๐ฎ๐ ๐ก ๐’๐š๐ฅ๐ข๐ฏ๐š ๐’๐ก๐š๐ซ๐ข๐ง๐ 

Continue reading “Kids Can Infer Close Relationships Through Saliva Sharing” »

Feb 1, 2022

RefSeek 404

Posted by in category: futurism

Just reminder, Google isnโ€™t everything.

www.refseek.com โ€” Academic Resource Search. More than a billion sources: encyclopedia, monographies, magazines.

www.woโ€ฆ See more.

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Feb 1, 2022

How โ€˜Dormantโ€™ Cells In The Aging Brain Contribute To Cognitive Decline

Posted by in categories: life extension, neuroscience

The Neuro-Network.

๐‡๐จ๐ฐ โ€˜๐ƒ๐จ๐ซ๐ฆ๐š๐ง๐ญโ€™ ๐‚๐ž๐ฅ๐ฅ๐ฌ ๐ˆ๐ง ๐“๐ก๐ž ๐€๐ ๐ข๐ง๐  ๐๐ซ๐š๐ข๐ง ๐‚๐จ๐ง๐ญ๐ซ๐ข๐›๐ฎ๐ญ๐ž ๐“๐จ ๐‚๐จ๐ ๐ง๐ข๐ญ๐ข๐ฏ๐ž ๐ƒ๐ž๐œ๐ฅ๐ข๐ง๐ž

๐˜พ๐™ค๐™œ๐™ฃ๐™ž๐™ฉ๐™ž๐™ซ๐™š ๐™™๐™š๐™˜๐™ก๐™ž๐™ฃ๐™š ๐™–๐™ฃ๐™™ ๐™›๐™ค๐™ง๐™œ๐™š๐™ฉ๐™ฉ๐™ž๐™ฃ๐™œ ๐™ฉ๐™๐™ž๐™ฃ๐™œ๐™จ ๐™–๐™จ ๐™ฌ๐™š ๐™œ๐™š๐™ฉ ๐™ค๐™ก๐™™๐™š๐™ง ๐™ž๐™จ ๐™–๐™ก๐™ข๐™ค๐™จ๐™ฉ ๐™– ๐™ง๐™ž๐™œ๐™๐™ฉ ๐™ค๐™› ๐™ฅ๐™–๐™จ๐™จ๐™–๐™œ๐™š. ๐˜ผ๐™ก๐™กโ€ฆ See more.

Continue reading “How โ€˜Dormantโ€™ Cells In The Aging Brain Contribute To Cognitive Decline” »

Jan 31, 2022

Scientists were able to regrow frog legs. Will it pave the way for human regeneration?

Posted by in categories: biotech/medical, life extension

A team of scientists at Tufts University and Harvard University โ€œhave brought us a step closer to the goal of regenerative medicineโ€ by using a drug cocktail to regrow a frogโ€™s amputated legs.

Peer-reviewed study: https://www.science.org/doi/10.1126/sciadv.abj2164


Scientists say they have been able to help frogs regrow their legs for the first time. The next step? Try the procedure on mammals.

Continue reading “Scientists were able to regrow frog legs. Will it pave the way for human regeneration?” »

Jan 29, 2022

Can deep sleep help devastating brain disorders? Scientists studying Parkinsonโ€™s want to find out

Posted by in categories: biotech/medical, health, neuroscience

๐™Ž๐™ก๐™š๐™š๐™ฅ ๐™ข๐™–๐™ฎ ๐™—๐™š ๐™ค๐™ฃ๐™š ๐™ค๐™› ๐™ฉ๐™๐™š ๐™ข๐™ค๐™จ๐™ฉ ๐™ฅ๐™ค๐™ฉ๐™š๐™ฃ๐™ฉ ๐™ข๐™š๐™™๐™ž๐™˜๐™ž๐™ฃ๐™š๐™จ ๐™›๐™ค๐™ง ๐™ฉ๐™๐™š ๐™—๐™ง๐™–๐™ž๐™ฃ, ๐™จ๐™˜๐™ž๐™š๐™ฃ๐™ฉ๐™ž๐™จ๐™ฉ๐™จ ๐™–๐™ง๐™š ๐™™๐™ž๐™จ๐™˜๐™ค๐™ซ๐™š๐™ง๐™ž๐™ฃ๐™œ, ๐™–๐™จ ๐™ฉ๐™๐™š๐™ฎ ๐™š๐™ญ๐™ฅ๐™ก๐™ค๐™ง๐™š ๐™ฉ๐™๐™š ๐™ž๐™ฃ๐™ฃ๐™š๐™ง ๐™ก๐™–๐™—๐™ฎ๐™ง๐™ž๐™ฃ๐™ฉ๐™๐™จ ๐™ค๐™› ๐™ฉ๐™๐™š ๐™ฉ๐™๐™ง๐™š๐™š-๐™ฅ๐™ค๐™ช๐™ฃ๐™™ ๐™ค๐™ง๐™œ๐™–๐™ฃ ๐™™๐™ช๐™ง๐™ž๐™ฃ๐™œ ๐™™๐™š๐™š๐™ฅ ๐™จ๐™ก๐™š๐™š๐™ฅ ๐™–๐™ฃ๐™™ ๐™™๐™ง๐™š๐™–๐™ข ๐™˜๐™ฎ๐™˜๐™ก๐™š๐™จ ๐™ž๐™ฃ ๐™—๐™ค๐™ฉ๐™ ๐™๐™š๐™–๐™ก๐™ฉ๐™ ๐™–๐™ฃ๐™™ ๐™™๐™ž๐™จ๐™š๐™–๐™จ๐™š.

The Neuro-Network.

๐‚๐š๐ง ๐๐ž๐ž๐ฉ ๐ฌ๐ฅ๐ž๐ž๐ฉ ๐ก๐ž๐ฅ๐ฉ ๐๐ž๐ฏ๐š๐ฌ๐ญ๐š๐ญ๐ข๐ง๐  ๐›๐ซ๐š๐ข๐ง ๐๐ข๐ฌ๐จ๐ซ๐๐ž๐ซ๐ฌ? ๐’๐œ๐ข๐ž๐ง๐ญ๐ข๐ฌ๐ญ๐ฌ ๐ฌ๐ญ๐ฎ๐๐ฒ๐ข๐ง๐  ๐๐š๐ซ๐ค๐ข๐ง๐ฌ๐จ๐งโ€™๐ฌ ๐ฐ๐š๐ง๐ญ ๐ญ๐จ ๐Ÿ๐ข๐ง๐ ๐จ๐ฎ๐ญ

Continue reading “Can deep sleep help devastating brain disorders? Scientists studying Parkinsonโ€™s want to find out” »

Jan 27, 2022

Anti-aging vaccine clears out dysfunctional cells that cause disease

Posted by in categories: biotech/medical, life extension

Many of the all-too-familiar symptoms of aging can be attributed to a build-up of senescent cells, those which have stopped dividing. In a new study, researchers in Japan have identified a protein specific to these cells and developed a vaccine that can clear them away, with tests on mice reducing the effects of aging.

Cells cannot keep dividing forever โ€“ eventually they accumulate too much DNA damage through environmental stress, so the body shuts them down and flags them to be cleared out by the immune system. This seems to be an evolutionary defense mechanism against cells turning cancerous.

However, even immune cells arenโ€™t immune from this process, and as they become senescent themselves the immune system gradually loses the ability to clear out senescent cells. As these inactive cells accumulate in the body, they contribute to symptoms of aging and the diseases that come with it.

Jan 26, 2022

WSU Master Class: Big Brains, Small Brains with Suzana Herculano-Houzel

Posted by in category: neuroscience

Pioneer Suzana Herculano-Houzel discusses the challenges and solutions of comparing brain size and function across species and shares her groundbreaking insights into the uniqueness, or lack thereof, of the human brain. #WorldSciU

This lecture was recorded on XXX at the World Science Festival in New York City.

Continue reading “WSU Master Class: Big Brains, Small Brains with Suzana Herculano-Houzel” »

Jan 26, 2022

WSU Master Class: Inflationary Cosmology with Alan Guth

Posted by in categories: cosmology, physics

Breakthrough Prize winner Alan Guth developed the theory of inflation to answer to our cosmic origins. Itโ€™s one of the most studied and debated theories in cosmology, with research propelling Guthโ€™s work to the forefront of scientific conversation.

In this Master Class, Professor Guth addresses what experiments could potentially rule out the BICEP2 results. Since recording this in 2017, the Planck spacecraft collected the data that Professor Guth anticipated, which shows that the initial observations were likely an artifact of interstellar dust, not primordial gravitational waves.

Continue reading “WSU Master Class: Inflationary Cosmology with Alan Guth” »

Jan 26, 2022

Modifying One Gene Allows Mice to Live 23% Longer

Posted by in categories: biotech/medical, life extension

โ€œThe change in life expectancy is significant, when you consider that an equivalent jump in human life expectancy would have us living on average until almost 120,โ€ lead researcher Haim Cohen of Bar-Ilan University told the Times of Israel.

A longer life: The average human life expectancy has doubled in just the past 200 years, thanks in no small part to scientific breakthroughs in medicine, nutrition, and disease.

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