Lifeboat Foundation

The 80,000 Hours Podcast features unusually in-depth conversations about the world’s most pressing problems and what you can do to solve them. Learn more, read the summary and find the full transcript on the 80,000 Hours website: https://80000hours.org/podcast/episodes/jan-leike-superalignment.

In July, OpenAI announced a new team and project: Superalignment. The goal is to figure out how to make superintelligent AI systems aligned and safe to use within four years, and the lab is putting a massive 20% of its computational resources behind the effort.

Continue reading “Jan Leike on OpenAI’s massive push to make superintelligence safe in 4 years or less” »

For C. Elegans, but but a cool use for the technology.

Magnesium Breakthrough 10% Discount _https://bit.ly/3O5tPfu_ Code Modern10 This video brought to you by BiOptimizers.
Here Prof Kaeberlein talks about the million molecule challenge and why he thought that it was necessary.

Continue reading “The Million Molecule Challenge To Find The Next Longevity Treatment | Prof Matt Kaeberlein Ep4” »

Most of us who’ve reached middle age have noticed a slowing in memory and cognition, but scientists don’t have a clear picture of the molecular changes that take place in the brain to cause it.

Now, a study in mice has determined that the most pronounced changes occur in the white matter, a type of nervous system tissue that’s integral to transmitting signals across the brain. The study also examined two treatments — caloric restriction and infusions of plasma from young mice — that affect certain regions of the brain, with the plasma appearing to slow the age-related decline.

Continue reading “Stanford Medicine-led research identifies gene ‘fingerprint’ for brain aging” »

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Humanity has evolved in the face of much hardship and turmoil, and invented technologies to aid us, but could an end to hardships be our undoing and cause us to devolve?

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Continue reading “Human Devolution Morlocks & C.H.U.D.s” »

The association between this mass concentration and the idea that atoms are empty stems from a flawed view that mass is the property of matter that fills a space. However, this concept does not hold up to close inspection, not even in our human-scale world. When we pile objects on top of each other, what keeps them separated is not their masses but the electric repulsion between the outmost electrons at their touching molecules. (The electrons cannot collapse under pressure due to the Heisenberg uncertainty and Pauli exclusion principles.) Therefore, the electron’s electric charge ultimately fills the space.

Anyone taking Chemistry 101 is likely to be faced with diagrams of electrons orbiting in shells.

In atoms and molecules, electrons are everywhere! Look how the yellow cloud permeates the entire molecular volume in Figure 1. Thus, when we see that atoms and molecules are packed with electrons, the only reasonable conclusion is that they are filled with matter, not the opposite.

The origin of the hominines is among the most hotly debated topics in paleoanthropology. The traditional view, ever since Darwin, holds that hominines and hominins originate in Africa, where the earliest hominins are found and where all extant non-human hominines live. More recently a European origin has been proposed, based on the phylogenetic analysis of late Miocene apes from Europe and Central Anatolia^1,2,3 The fossils described here attest to a lengthy history of hominines in Europe, with multiple taxa in the eastern Mediterranean known for at least 2.3 Ma^4,5,6,7 Our phylogenetic analysis, based on the new specimens described here and a large sample of other fossil and extant hominoids (Supplementary Note 1, Tables 1, 2), supports previous research confirming the hominine status of the eastern Mediterranean apes^{2,3,8,9,10,11,12,13,14,15,16,17,18,19,20} Our most parsimonious phylogenetic results suggest that hominines in the eastern Mediterranean evolved from dryopithecins in central and western Europe, though there are alternative interpretations^21,22,23,24. Either way, the oldest known hominines are European. They may have dispersed into Europe from ancestors in Africa, only to become extinct²² However, the more likely and more parsimonious interpretation is that hominines evolved over a lengthy period in Europe and dispersed into Africa before 7 Ma.

For some time, the only known late Miocene ape from Anatolia was Ankarapithecus, which is alternatively described as a stem hominid or a pongine^25,26,27, but not a hominine. It is easily distinguished from Our anopithecus and Graecopithecus from Greece and Bulgaria^25,26,27 In 2007, a new species of Our anopithecus was described from Çorakyerler in central Anatolia²⁸. Since then, thousands of vertebrate fossils have been recovered at Çorakyerler, including a well-preserved ape partial cranium²⁹ (Fig. 1) The O. turkae holotype, a fragmented palate, was originally distinguished from O. macedoniensis in its shorter premaxilla, narrower palate, morphologically similar (homomorphic) upper premolars (as opposed to P3 being more triangular than P4), smaller male canines and possibly larger size²⁸. However, recovery of the new cranium and our reanalysis of the published material requires a reassessment of this conclusion and justifies the naming of a new genus of Miocene hominine.

A team of physicists and geologists at CEA DAM-DIF and Universit´e Paris-Saclay, working with a colleague from ESRF, BP220, F-38043 Grenoble Cedex and another from the European Synchrotron Radiation Facility, has succeeded in synthesizing a single-crystalline iron in a form that iron has in the Earth’s core.

In their paper published in the journal Physical Review Letters, the group describes how they used an experimental approach to synthesize pure single-crystalline ε-iron and possible uses for the material.

In trying to understand Earth’s internal composition, scientists have had to rely mostly on seismological data. Such studies have led scientists to believe that the core is solid and that it is surrounded by liquid. But questions have remained. For example, back in the 1980s, studies revealed that seismic waves travel faster through the Earth when traveling pole to pole versed equator to equator, and no one could explain why.

When supermassive black holes barrel toward collision, they can reach speeds of up to 1/10th the speed of light, new research suggests.

New bionic hand with better move of fingers.

Successful testing of the bionic hand has already been conducted on a patient who lost his arm above the elbow.

In a world first, surgeons and engineers have developed a new bionic hand that allows users with arm amputations to effortlessly control each finger as though it was their own body.

Continue reading “New bionic hand allows amputees to effortlessly control fingers” »