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Aug 17, 2023

How did supermassive black holes get so big so fast just after the Big Bang?

Posted by in category: cosmology

Finding supermassive black holes with masses billions of times greater than the sun under a billion years after the Big Bang has scientists confused how these cosmic titans got so big so quickly.

Aug 17, 2023

Durham gene editing firm strikes big deal; it’s ‘right-sized;’ 80 employees exit

Posted by in categories: bioengineering, biotech/medical, finance

DURHAM – A big licensing deal potentially worth hundreds of millions of dollars with an Austrlia-based company at the same time also has triggered what Precision Biosciences calls a “right-sized” organization of the company.

“Prior to the announcement, we had 190 employees, with 110 going forward with Precision. Most of the 80 employees went with Imugene, with the remainder parting ways with a reduction in force,” Mei Burris, director of investor relations and finance for the company,” told WRAL TechWire.

What “right-sized” means was not immediately explained in the company’s announcement Tuesday night after the markets closed. The company’s stock is trading at under $1 and it lost $12 million in its most recent quarter ending June 30.

Aug 17, 2023

There’s a simple way to improve your decision-making, according to a cognitive scientist

Posted by in category: neuroscience

Have to make a hard choice? Don’t just compare options. Do this instead.

Aug 17, 2023

Complexity Theory’s 50-Year Journey to the Limits of Knowledge

Posted by in category: computing

“There’s no road map,” said Michael Sipser, a veteran complexity theorist at the Massachusetts Institute of Technology who spent years grappling with the problem in the 1980s. “It’s like you’re going into the wilderness.”

It seems that proving that computational problems are hard to solve is itself a hard task. But why is it so hard? And just how hard is it? Carmosino and other researchers in the subfield of meta-complexity reformulate questions like this as computational problems, propelling the field forward by turning the lens of complexity theory back on itself.

Aug 17, 2023

Why Isaac Newton’s laws still give physicists a lot to think about

Posted by in category: physics

The apparent equivalence of gravitational mass to inertial mass is a remarkable and beautiful feature of the cosmos, with a deep implication, says Chanda Prescod-Weinstein

By Chanda Prescod-Weinstein

Aug 17, 2023

Mathematics Has a Biological Origin, Study Reveals

Posted by in categories: biological, mathematics

Everyone knows that arithmetic is true: 2 + 2 = 4.

But surprisingly, we don’t know why it’s true.

By stepping outside the box of our usual way of thinking about numbers, my colleagues and I have recently shown that arithmetic has biological roots and is a natural consequence of how perception of the world around us is organised.

Aug 17, 2023

Schizophrenia Drugs May Have Been Off Target For Decades, Study Finds

Posted by in categories: biotech/medical, chemistry, neuroscience

A study that peered into live mouse brains suggests for nearly 70 years we’ve been targeting the wrong neurons in our design of antipsychotic drugs.

Untangling the vast web of brain cells and determining how drugs work upon them is a tough task. Using a miniature microscope and fluorescent tags, a team of researchers led by Northwestern University neuroscientist Seongsik Yun discovered that effective antipsychotic drugs cling to a different type of brain cell than scientists originally thought.

Just like research suggesting depression might not be a chemical imbalance in serotonin levels, our understanding of schizophrenia treatments may need a rethink if widely-used antipsychotics are targeting different neurons than expected.

Aug 17, 2023

Scientists Uncover Source of Unusual Deformation in Earth’s Largest Continental Rift

Posted by in category: computing

Computer simulations confirm that the African Superplume causes the unusual deformations and rift-parallel seismic anisotropy detected below the East African Rift System.

Continental rifting involves a combination of stretching and fracturing that penetrates deep within the Earth, explains geophysicist D. Sarah Stamps. This process pertains to the elongation of the lithosphere, Earth’s rigid outer layer. As it becomes more taut, the lithosphere’s upper sections undergo brittle changes, leading to rock fractures and earthquakes.

Stamps, who studies these processes by using computer modeling and GPS.

Aug 17, 2023

Scientists Successfully Recreate and Mathematically Validate Two Molecular Languages at the Origin of Life

Posted by in categories: biotech/medical, chemistry, nanotechnology

Canadian researchers at the University of Montreal have successfully recreated and mathematically confirmed two molecular languages at the origin of life.

Their groundbreaking findings, recently published in the Journal of American Chemical Society, pave the way for advancements in nanotechnologies, offering potential in areas like biosensing, drug delivery, and molecular imaging.

Living organisms are made up of billions of nanomachines and nanostructures that communicate to create higher-order entities able to do many essential things, such as moving, thinking, surviving, and reproducing.

Aug 17, 2023

Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes

Posted by in categories: biotech/medical, genetics

Genome-wide association analyses of magnetic resonance imaging data describe the genetic architecture of 13 cortical phenotypes at both global and regional levels, implicating neurodevelopmental and constrained genes.