Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog – Page 1,834

MD Anderson researchers identify molecule that reduces age-related inflammation and improves brain and muscle function in preclinical models.

MD Anderson News Release June 21, 2024

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring…

The study, published today in Cell, identified a small molecule compound that restores physiological levels of telomerase reverse transcriptase (TERT), which normally is repressed with the onset of aging. Maintenance of TERT levels in aged lab models reduced cellular senescence and tissue inflammation, spurred new neuron formation with improved memory, and enhanced neuromuscular function, which increased strength and coordination.

The researchers show that TERT functions not only to extend telomeres, but also acts as a transcription factor to affect the expression of many genes directing neurogenesis, learning and memory, cellular senescence, and inflammation.

Read more | >

In pausing to think before making an important decision, we may imagine the potential outcomes of different choices we could make. While this “mental simulation” is central to how we plan and make decisions in everyday life, how the brain works to accomplish this is not well understood.

An international team of scientists has now uncovered neural mechanisms used in planning. Its results, published in the journal Nature Neuroscience, suggest that an interplay between the brain’s prefrontal cortex and hippocampus allows us to imagine future outcomes in order to guide our decisions.

“The prefrontal cortex acts as a ‘simulator,’ mentally testing out possible actions using a cognitive map stored in the hippocampus,” explains Marcelo Mattar, an assistant professor in New York University’s Department of Psychology and one of the paper’s authors.

Read more | >

Back in June, YouTube quietly made a subtle but significant policy change that, surprisingly, benefits users by allowing them to remove AI-made videos that simulate their appearance or voice from the platform under YouTube’s privacy request process.

First spotted by TechCrunch, the revised policy encourages affected parties to directly request the removal of AI-generated content on the grounds of privacy concerns and not for being, for example, misleading or fake. YouTube specifies that claims must be made by the affected individual or authorized representatives. Exceptions include parents or legal guardians acting on behalf of minors, legal representatives, and close family members filing on behalf of deceased individuals.

According to the new policy, if a privacy complaint is filed, YouTube will notify the uploader about the potential violation and provide an opportunity to remove or edit the private information within their video. YouTube may, at its own discretion, grant the uploader 48 hours to utilize the Trim or Blur tools available in YouTube Studio and remove parts of the footage from the video. If the uploader chooses to remove the video altogether, the complaint will be closed, but if the potential privacy violation remains within those 48 hours, the YouTube Team will review the complaint.

Read more | >

SMU and the University of Rhode Island have patented an inexpensive, easy-to-use method to create solid-state nanopores (SSNs), while also making it possible to self-clean blocked nanopores.

The technique called chemically-tuned controlled dielectric breakdown (CT-CDB) addresses two key problems that have kept solid-state nanopores – which are too tiny for the human eye to see – from being used more often to build biosensors that can measure biological and chemical reactions of a given sample.

Biosensors have widespread medical applications, enabling rapid, early and effective disease diagnosis and monitoring.

Read more | >