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In the digital age, where entertainment is but a click away, a silent yet powerful transformation is underway. Streaming companies, the vanguards of this digital entertainment era, are not just delivering content; they’re crafting experiences, and artificial intelligence (AI) is their most adept tool. Let us explore how AI is not just changing, but revolutionizing the way we consume media.

Gone are the days of aimlessly browsing channels to find something to watch. AI in streaming services is like a discerning director, understanding and curating content to fit the unique tastes of each viewer. It’s an era where your streaming service knows what you want to watch, sometimes even before you do. The great power of AI is personalization, where organizations can create unique user journeys. At the core of AI’s integration into streaming is personalization. Netflix, the colossus of streaming, employs AI algorithms to recommend movies and shows based on your viewing history. However, generally, these recommendation engines based on historical presences have muted value. Traditional metrics leverage past viewing information or collaborative filtering to make content recommendations. However, customer feedback has shown these are imperfect fits in the age of data for precision product-market fit.

General-purpose humanoid robots using AI are advancing and increasingly gaining investment support to perform tasks that humans do easily.


Humanoid AI smart robots are accelerating with major investments from automotive giants BMW, Honda, Hyundai, Mercedes Benz and Tesla, to name a few. Will this growth and interest accelerate approval of a new 32-hour work week bill earlier?

The manufacturing process for personalized T-cell therapies hardly begins before it stalls. Why? Right at the start, there is a severe bottleneck: the need to identify patient-derived, tumor-reactive T-cell receptors (TCRs).

To overcome this bottleneck, scientists at the German Cancer Research Center (DKFZ) and the University Medical Center Mannheim have developed predicTCR, a machine learning classifier. According to the scientists, it can identify individual tumor-reactive tumor-infiltrating lymphocyte (TILs) in an antigen-agnostic manner based on single-TIL RNA sequencing.

The scientists also assert that prediTCR can halve the time it takes to get past the bottleneck, helping to reduce the overall time needed to make a personalized T-cell therapy for cancer patients. Since the overall time is at least six months, any reduction in the time needed to complete any manufacturing step is welcome.

Until now, it was not clear how hepatocytes were assigned tasks related to their localization. Researchers at the Spanish National Cancer Research Center (CNIO) have discovered that a gene, mTOR, is responsible for organizing the hepatocyte position map.

They also found that what triggers hepatocyte specialization is feeding after birth. The difference is marked by how nutrients reach the organism before and after birth: with no interruptions through the umbilical cord in one case, or in an intermittent fashion –when eating– in the other. The alternation of periods with and without available nutrients activates the mTOR gene and causes the hepatocytes to specialize, which completes the maturation of the liver.

Short version: You should be taking NAD boosters.


Professor Danica Chen from UC Berkeley presents ways to protect mitochondria and reverse stem cell aging in this video.
https://pubmed.ncbi.nlm.nih.gov/36255
https://pubmed.ncbi.nlm.nih.gov/32504
https://www.sciencedirect.com/science
https://pubmed.ncbi.nlm.nih.gov/37146
https://pubmed.ncbi.nlm.nih.gov/37919

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ICYMI: March 15, 2024 was World Sleep Day.

Sleep is super important for the brain — that’s when memories can be turned from short term to long term memories. And during sleep the brain’s cleaning system is working at full capacity! 🫧🧼🚿💦


During sleep, our brains are busy consolidating memories and removing waste to keep our minds sharp. Recent findings from Yale on sleep hygiene and more.

NEW ORLEANS, March 18, 2024 — Doctors have long prescribed exercise to improve and protect health. In the future, a pill may offer some of the same benefits as exercise. Now, researchers report on new compounds that appear capable of mimicking the physical boost of working out — at least within rodent cells. This discovery could lead to a new way to treat muscle atrophy and other medical conditions in people, including heart failure and neurodegenerative disease.

The researchers will present their results today at the spring meeting of the American Chemical Society (ACS). ACS Spring 2024 is a hybrid meeting being held virtually and in person March 17–21; it features nearly 12,000 presentations on a range of science topics.

“We cannot replace exercise; exercise is important on all levels,” says Bahaa Elgendy, the project’s principal investigator who is presenting the work at the meeting. “If I can exercise, I should go ahead and get the physical activity. But there are so many cases in which a substitute is needed.”