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A newly developed “GPS nanoparticle” injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State. They tested their approach in human cell lines and in mice to effectively knock down a cancer-causing gene, reporting that the technique may potentially offer a more precise and effective treatment for notoriously hard-to-treat basal-like breast cancers.

An international team of researchers has succeeded in “filming” the activation of an important receptor. They froze the involved molecules at different points in time and photographed them under the electron microscope. They were then able to place these still images in sequence. This sequence shows step by step which spatial changes the receptor undergoes when it is activated.

To combine two low-energy photons into one high-energy photon efficiently, the energy must be able to hop freely, but not too quickly, between randomly oriented molecules of a solid. This Kobe University discovery provides a much-needed design guideline for developing materials for more efficient PV cells, displays, or even anti-cancer therapies.

Light of different colors has different energies and is therefore useful for very different things. For the development of more efficient PV cells, OLED displays, or anti-cancer therapies, it is desirable to be able to upcycle two low-energy photons into a high-energy , and many researchers worldwide are working on materials for this up-conversion.

During this process, light is absorbed by the material, and its energy is handed around among the material’s as a so-called “triplet exciton.” However, it was unclear what allows two triplet excitons to efficiently combine their energies into a different excited state of a single molecule that then emits a high-energy photon, and this knowledge gap has been a serious bottleneck in the development of such materials.

A critical molecule for the metabolism of living organisms has been synthesized for the first time by University of Hawaiʻi at Mānoa researchers at low temperatures (10 K) on ice coated nanoparticles mimicking conditions in deep space, marking a “cool” step in advancing our understanding of the origins of life.

LG Electronics may no longer be a household name in smartphones, but it still sees a big future in gadgets like robots. Today, the company confirmed a $60 million investment in Bear Robotics, the California startup that makes artificial intelligence–powered server robots (autonomous tray towers on wheels that are meant to replace waiters) for restaurants and other venues. With the investment, LG Electronics becomes Bear’s largest shareholder.

Bear’s last fundraise in 2022 valued the company at just over $490 million post-money, per PitchBook data. It’s not clear what the valuation is for this latest investment, but the last year has not been a great one for startups in the space.

On the other hand, the current vogue for all things AI, and the general advances that are coming with that, are giving robotics players a fillip — see yesterday’s Covariant news, for another example. Still, it’s not clear what Bear hopes to tackle next with the basic trays-on-wheels form factor that it has adopted for its flagship Servi robots.