Lifeboat Foundation

Back in 1956, Denham Harman proposed that the aging is caused by the build up of oxidative damage to cells, and that this damage is caused by free radicals which have been produced during aerobic respiration [1]. Free radicals are u nstable atoms that have an unpaired electron, meaning a free radical is constantly on the look-out for an atom that has an electron it can pinch to fill the space. This makes them highly reactive, and when they steal atoms from your body’s cells, it is very damaging.

Longevity. Technology: As well as being generated in normal cell metabolism, free radicals can be acquired from external sources (pollution, cigarette smoke, radiation, medication, &c) and while the free radical theory of aging has been the subject of much debate [2], the understanding of the danger free radicals pose led to an increase in the public’s interest in superfoods, vitamins and minerals that were antioxidants – substances that have a spare electron which they are happy to give away to passing free radicals, thus removing them from the danger equation.

But before you reach for the blueberries, it is important to know that, as so often in biology, the story is not black and white. Like a misunderstood cartoon villain, free radicals have a beneficial side, too – albeit in moderation. Free radicals generated by the cell’s mitochondria are beneficial in wound-healing, and others elsewhere act as important signal substances. Used as weapons by the body’s defense system, free radicals destroy invading pathogenic microbes to prevent disease.

The quantum nature of interactions between elementary particles allows drawing non-trivial conclusions even from processes as simple as elastic scattering. The ATLAS experiment at the LHC accelerator reports the measurement of fundamental properties of strong interactions between protons at ultra-high energies.

The physics of billiard ball collisions is taught from early school years. In a good approximation, these collisions are elastic, where both momentum and energy are conserved. The scattering angle depends on how central the collision was (this is often quantified by the impact parameter value—the distance between the centers of the balls in a plane perpendicular to the motion). In the case of a small impact parameter, which corresponds to a highly central collision, the scattering angles are large. As the impact parameter increases, the scattering angle decreases.

In particle physics, we also deal with elastic collisions, when two particles collide, maintaining their identities, and scatter a certain angle to their original direction of motion. Here, we also have a relationship between the collision parameter and the scattering angle. By measuring the scattering angles, we gain information about the spatial structure of the colliding particles and the properties of their interactions.

The first comprehensive study of electric-field-induced polarization switching in wurtzites reveals an atomic-scale switching pathway with potential electronics applications.

All biological systems are wildly disordered. Yet somehow, that disorder enables plant photosynthesis to be nearly 100% efficient.

We are pleased to announce Claude 2, our new model. Claude 2 has improved performance, longer responses, and can be accessed via API as well as a new public-facing beta website, claude.ai. We have heard from our users that Claude is easy to converse with, clearly explains its thinking, is less likely to produce harmful outputs, and has a longer memory. We have made improvements from our previous models on coding, math, and reasoning. For example, our latest model scored 76.5% on the multiple choice section of the Bar exam, up from 73.0% with Claude 1.3. When compared to college students applying to graduate school, Claude 2 scores above the 90th percentile on the GRE reading and writing exams, and similarly to the median applicant on quantitative reasoning.

Think of Claude as a friendly, enthusiastic colleague or personal assistant who can be instructed in natural language to help you with many tasks. The Claude 2 API for businesses is being offered for the same price as Claude 1.3. Additionally, anyone in the US and UK can start using our beta chat experience today.

Continue reading “Claude 2: We are pleased to announce Claude 2, our new model” »

The recent rise of powerful large language models (LLMs) has revolutionized the field of natural language processing (NLP).

The performance of these generative models is largely dependent on users’ prompts, which are becoming increasingly detailed and complex.

A Google Trends search reveals a hundredfold increase in popularity for the term “prompt engineering” over the last six months, and social media is teeming with novel prompting tips and templates.

The European Southern Observatory continues to build the largest telescope in the world, the Extremely Large Telescope (ELT). Construction of the telescope began in 2014 with flattening the top of a mountain named Cerro Armazones in Chile’s Atacama Desert.

ESO just announced that progress on construction has crossed the 50% mark. The remaining work should take another five years. When it finally comes online in 2028, the telescope will have a 39-meter (128 ft) primary mirror of 798 hexagonal segments, making it the largest telescope in the world for visible and infrared light. The new telescope should help to answer some of the outstanding questions about our Universe, such as how the first stars and galaxies formed, and perhaps even be able to take direct images of extrasolar planets.

Continue reading “The Biggest Telescope in the World is Half Built” »

Tesla CEO Elon Musk claims the brand’s cars can swim for short periods of time, implying that owners can escape floods or drive past water crossings.

Our universe could be twice as old as current estimates, according to a new study that challenges the dominant cosmological model and sheds new light on the so-called “impossible early galaxy problem.”

“Our newly-devised model stretches the galaxy formation time by a several billion years, making the universe 26.7 billion years old, and not 13.7 as previously estimated,” says author Rajendra Gupta, adjunct professor of physics in the Faculty of Science at the University of Ottawa.

For years, astronomers and physicists have calculated the age of our universe by measuring the time elapsed since the Big Bang and by studying the oldest stars based on the redshift of light coming from distant galaxies. In 2021, thanks to new techniques and advances in technology, the age of our universe was thus estimated at 13.797 billion years using the Lambda-CDM concordance model.