283,119 views • Mar 13, 2024 • ✪ Members first on March 12, 2024 • #sciencenews #technology #science
But the technology for using bridge RNA in genome editing is still in the early stages. Hsu’s team has demonstrated this system only in bacteria, though Hsu says he is optimistic that efforts to adapt the approach to work in mammalian cells will succeed. Chen says this system’s efficiency may not be as good as CRISPR’s is now but that improvements will come with time.
The wearables market has been dominated, so far, by smartwatches and fitness trackers. The first Apple Watch was launched in April 2015, and wearable technology now includes jewelry that tracks your steps and notifies you of an incoming call, VR headsets for gamers, earbuds, smart glasses with Internet access, smart clothing integrated with electronic devices and a range of health monitors.
But the world’s first eyelid wearable device opens up a whole new world of opportunity.
Blink Energy’s device weighs just 0.4 grams (0.014 ounces) — less than half the weight of a paperclip – and is fitted to one eyelid. You barely notice it, says Bar-On. “After two minutes you forget it’s there.”
Electronic waste, or e-waste, is a rapidly growing global problem, and it’s expected to worsen with the production of new kinds of flexible electronics for robotics, wearable devices, health monitors, and other new applications, including single-use devices.
A new kind of flexible substrate material developed at MIT, the University of Utah, and Meta has the potential to enable not only the recycling of materials and components at the end of a device’s useful life, but also the scalable manufacture of more complex multilayered circuits than existing substrates provide.
The development of this new material is described in the journal RSC Applied Polymers (“Photopatternable, Degradable, and Performant Polyimide Network Substrates for E-Waste Mitigation”), in a paper by MIT Professor Thomas J. Wallin, University of Utah Professor Chen Wang, and seven others.
Researchers led by the University of California, Irvine have discovered how the TREM2 R47H genetic mutation causes certain brain areas to develop abnormal protein clumps, called beta-amyloid plaques, associated with late-onset Alzheimer’s disease. Leveraging single-cell Merfish spatial transcriptomics technology, the team was able to profile the effects of the mutation across multiple cortical and subcortical brain regions, offering first-of-their-kind insights at the single-cell level.
The study, published in Molecular Psychiatry, compared the brains of normal mice and special mouse models that undergo changes like those in humans with Alzheimer’s.
Findings revealed that the TREM2 mutation led to divergent patterns of beta-amyloid plaque accumulation in various parts of the brain involved in higher-level functions such as memory, reasoning and speech. It also affected certain cell types and their gene expression near the plaques.
Experiments that test physics and philosophy “as a single whole” may be our only route to surefire knowledge about the universe.
With the first CRISPR–Cas9 gene therapy now approved, scientists are turning to newer editing technologies to produce safer, faster and better treatments for genetic diseases.
When the European Space Agency launched the Gaia spacecraft to map stars, it encountered problems from a solar storm and space dust. Its electronics and measurements were impacted by these issues, which raised data inaccuracies. To overcome these issues, teams are collaborating remotely.
Figure 2 can pick up objects as heavy as 55 pounds and put parts in place accurately, down to the millimeter. It was created by Figure AI, a startup backed by OpenAI, Jeff Bezos, Nvidia, and Microsoft.
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