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New CRISPR system for gene silencing doesn’t rely on cutting DNA

Scientists from Vilnius University’s (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA. This research, led by Prof. Patrick Pausch and published in the journal Nature Communications, reveals a new way to silence genes that is akin to pressing a “pause” button on certain genetic instructions within cells.

UP Aerospace and Los Alamos lab achieve successful suborbital launch at Spaceport America

In Nijmegen, Netherlands, researchers have installed the world’s first microscope capable of live imaging of biological processes in such detail that moving protein complexes are visible. This new microscopic technique was developed by researchers led by Nico Sommerdijk from Radboud university medical center. As a demonstration of this innovative technique, Sommerdijk is now showcasing how arterial calcification begins.

Induced pluripotent stem cell-derived macrophages as a platform for modelling human disease

Macrophages are associated with many human diseases but are challenging to study in vivo. Here, Ginhoux and colleagues discuss how iMacs — macrophages generated from induced pluripotent stem (iPS) cells — can enable disease modelling, including through the use of patient-derived iPS cells and 3D organoid co-culture systems. Ultimately, these iMac-based approaches can improve our understanding of macrophage biology in both health and disease.

Breakthrough Tech Captures and Destroys “Forever Chemicals” in a Single Process — a Game-Changer for Clean Water

Researchers created a single-step device using redox electrodialysis and electrosorption to capture and destroy diverse PFAS chemicals, aiming to address contamination in water and industrial wastewater.

A study from the University of Illinois Urbana-Champaign is the first to introduce an electrochemical method capable of capturing, concentrating, and destroying diverse PFAS chemicals—including the increasingly common ultra-short-chain PFAS—in water, all in a single process. This breakthrough holds promise for tackling the mounting industrial challenge of PFAS contamination, especially within semiconductor manufacturing.

A previous U. of I. study showed that short-and long-chain PFAS can be removed from water using electrochemically driven adsorption, referred to as electrosorption, but this method is ineffective for ultra-short-chain molecules because of their small size and different chemical properties. The new study, led by Illinois chemical and biomolecular engineering professor Xiao Su, combines a desalination filtration technology, called redox electrodialysis, with electrosorption in a single device to address the problems associated with capturing the complete PFAS size spectrum.

Alaska volcanologists continue to track unrest at Mount Spurr

Scientists continue to monitor Mount Spurr, a volcano to the west of Anchorage and a huge chunk of the state’s population, after signs of unrest this spring, and again in the fall.

The Alaska Volcano Observatory raised its color code for Spurr to yellow, or “advisory” status, Oct. 16.

The observatory’s Scientist in Charge, Matt Haney, says that was after seismometers picked up an increased number of small earthquakes at the volcano and GPS sensors showed it was swelling up.

Heavy-ion run at the LHC begins

The Large Hadron Collider (LHC) is like an immensely powerful kitchen, designed to cook up some of the rarest and hottest recipes in the universe, like the quark–gluon plasma, a state of matter known to have existed shortly after the Big Bang. While the LHC mostly collides protons, once a year it collides heavy ions—such as lead nuclei—a key ingredient for preparing this primordial soup.