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In this episode of the Longevity Optimization Podcast, Dr. DeGray discusses groundbreaking research in aging and longevity, focusing on combination therapies, the hallmarks of aging, and the potential of stem cell and gene therapies. He emphasizes the importance of rejuvenation over merely slowing aging and explores the role of the immune system in health. The conversation also touches on biological age testing, lifestyle factors, and the future of gene therapy in enhancing longevity.

Aubrey de Grey is a British biomedical gerontologist and the founder of the SENS Research Foundation. He is a leading advocate for regenerative medicine, focusing on reversing the effects of aging by repairing cellular damage. Known for his bold vision of life extension, de Grey believes that with advanced therapies, humans could significantly extend their lifespan. He is the co-author of Ending Aging, and his work continues to shape the future of longevity science.

Takeaways.

Combination therapies are crucial for understanding aging.
Rejuvenation may be easier than slowing down aging.
Stem cell therapies hold great promise for the future.
The immune system plays a significant role in aging.
Biological age testing can provide insights into health.
Gene therapy is a promising avenue for longevity research.
Lifestyle factors have limited impact on lifespan extension.
Understanding the hallmarks of aging is essential for interventions.
Preventative maintenance is key to longevity.
The future of aging research is bright with new technologies.

Chapters.

00:00 Introduction to Longevity and Aging Research.

Imagine a tiny, soft robot that could change the way medicine is delivered to targeted areas in the body.


A team of scientists at NTU has developed grain-sized soft robots that can be controlled using magnetic fields for targeted drug delivery, paving the way to possible improved therapies in future.

The new soft robot developed by engineers at NTU’s School of Mechanical and Aerospace Engineering (MAE) was reported in a paper published in the journal Advanced Materials.

The study is believed to be the first reported instance of miniature robots that can transport up to four different drugs and release them in reprogrammable orders and doses.

Virtual worlds, ChatGPT, and AI seem to be all the rage in 2024, with all sorts of developments shaking up not just the technology space, but having wider implications for medicine, politics, and even the judicial system. Now, researchers from Swiss startup FinalSpark have combined a virtual world with tiny human mini brains and built a two-way con…

Professor Michael Levin explores the revolutionary concept of diverse intelligence, demonstrating how cognitive capabilities extend far beyond traditional brain-based intelligence. Drawing from his groundbreaking research, he explains how even simple biological systems like gene regulatory networks exhibit learning, memory, and problem-solving abilities. Levin introduces key concepts like “cognitive light cones” — the scope of goals a system can pursue — and shows how these ideas are transforming our approach to cancer treatment and biological engineering.

Brush up on your physics knowledge with Brilliant! First 30 days are free and 20% off the annual premium subscription when you use our link ➜ https://brilliant.org/sabine.

Mathematician and Computer Scientist Stephen Wolfram wants to do no less than revolutionising physics. He wants to do it with computer code that gives rise to all the fundamental laws of nature that we know and like — and maybe more. Unfortunately, Einstein’s theories of general relativity inherently clash with how computers work. And yet, he and his team might have found a clever way around this problem.

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1GITEX Global 2024 and IROS 2024 became true gateways to the future of technology, bringing together the most advanced innovations in artificial intelligence, robotics, and transportation under one roof. At the forefront of GITEX was the unique Nissan Hyperforce concept, an electric vehicle with an incredible 1,360 horsepower, capable of accelerating from 0 to 100 km/h in just 2 seconds. This electric supercar not only stunned with its speed but also with its futuristic design, reminiscent of the iconic Batmobile. With its advanced driving modes, R and GT, drivers can switch between a sporty and comfortable driving experience.

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0:00 Exhibitions in the United Arab Emirates.
0:34 GITEX GLOBAL 2024
0:47 Nissan Hyper Force supercar.
1:43 Italdesign’s Quintessenza concept car.
2:39 Ameca robot.
3:15 Robot bartender.
3:38 Airscooter by Zapata.
4:13 Autonomous Patrol of the Future by Dubai Police.
5:09 Tesla Cybertruck.
6:01 All-terrain delivery vehicles from Mobinn.
6:20 Cadillac Electric Flyer.
7:03 Drones by Multi Level Group.
7:32 Xpeng Aeroht Flying Car.
8:18 New humanoid robot Kepler.
8:42 ZainTECH Drones.
9:04 Robo-charging electric cars.
9:43 Odigo robot with AI
10:26 IROS 2024
11:02 Obstacle course for four-legged robots.
11:41 Robofootball on IROS 2024
12:32 High Torque Robotics.
13:03 Unitree robots.
13:39 Nimble Direct Drive Robots.
14:16 Elephant Robotics.
14:47 Humanoid robots on display.
15:14 DexNex teleoperated system.
15:47 Hubot robot.

In addition, GITEX 2024 showcased the latest flying car concepts. Among them was a model capable of unfolding its blades and taking off in just two minutes, making it the perfect vehicle for fast, seamless travel both on the road and in the sky. The exhibition also featured other cutting-edge innovations, such as autonomous patrol cars equipped with drones and robotic bartenders that serve drinks without lines or fuss.

IROS 2024, held in Abu Dhabi, was equally impressive, giving a glimpse into the future of robotics. Highlights included thrilling competitions between robot dogs and humanoid robots, as well as demonstrations of new robots capable of running, jumping, and even performing complex acrobatic tricks. Autonomous robots designed for patrolling and delivery, capable of navigating routes and recognizing objects in the toughest conditions, also drew significant attention.

Both exhibitions revealed how robotics and AI are increasingly influencing our everyday lives, offering solutions for safety, transportation, and even entertainment. Unique projects, such as autonomous drones for agriculture and firefighting, and robotic systems for smart cities, are already reshaping urban spaces. With the technologies presented at GITEX and IROS, the future is closer than ever. Subscribe to our channel to stay updated on the latest innovations and events in the world of high-tech.