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Nov 26, 2023

Man spends millions to attempt to reverse aging

Posted by in categories: innovation, life extension

Bryan Johnson, 45, is using his life as a science experiment to see how long he can live and to reverse signs of aging as he goes. NBC News’ Gadi Schwartz reports.

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Nov 26, 2023

What the World Will Be Like in 2123

Posted by in categories: biotech/medical, media & arts, transportation

Let’s take a leap into the future, shall we? In 2,123, envision a world where technology is seamlessly integrated into every aspect of our lives. Flying cars might not be the norm, but sustainable modes of transportation dominate the scene, with eco-friendly solutions at the forefront. Advanced medical breakthroughs have extended human life expectancy, and perhaps we’ve even cracked the code on combating climate change. Social structures may have evolved, embracing inclusivity and diversity. It’s a realm where innovation and a collective global effort have paved the way for a balanced and interconnected planet. 🌐🚀🔮

Credit:
IKAROS: Andrzej Mirecki, CC BY-SA 3.0 https://creativecommons.org/licenses/by-sa/3.0/, https://commons.wikimedia.org/wiki/File: IKAROS_solar_sail.jpg.
Press Conference: ESO, CC BY 4.0 https://creativecommons.org/licenses/by/4.0/, https://commons.wikimedia.org/wiki/File: Press_Conference_at_ESO_HQ2.tif.

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Nov 26, 2023

Oral Microbiome Tests #8 and 9: Serratia marcescens Is Still A Problem

Posted by in categories: biotech/medical, genetics, life extension

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Nov 26, 2023

‘Huge egos are in play’: behind the firing and rehiring of OpenAI’s Sam Altman

Posted by in category: robotics/AI

The surprise sacking of the AI venture’s CEO was followed by a near mutiny at the company and his reinstatement.

Nov 26, 2023

How Memory Makes Us and Breaks Truth: The Rashomon Effect and the Science of How Memories Form and Falter in the Brain

Posted by in categories: neuroscience, science

It is already disorienting enough to accept that our attention only absorbs a fraction of the events and phenomena unfolding within and around us at any given moment. Now consider that our memory only retains a fraction of what we have attended to in moments past. In the act of recollection, we take these fragments of fragments and try to reconstruct from them a totality of a remembered reality, playing out in the theater of the mind — a stage on which, as neuroscientist Antonio Damasio has observed in his landmark work on consciousness, we often “use our minds not to discover facts, but to hide them.”

We do this on the personal level — out of such selective memory and by such exquisite exclusion, we compose the narrative that is the psychological pillar of our identity. We do it on the cultural level — what we call history is a collective selective memory that excludes far more of the past’s realities than it includes. Borges captured this with his characteristic poetic-philosophical precision when he observed that “we are our memory… that chimerical museum of shifting shapes, that pile of broken mirrors.” To be aware of memory’s chimera is to recognize the slippery, shape-shifting nature of even those truths we think we are grasping most firmly.

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Nov 26, 2023

Weaponizing Brain Science: Neuroweapons — Part 2 of 2

Posted by in categories: biotech/medical, military, neuroscience, science

https://www.hdiac.org/podcast/neuroweapons-part-2/

The second installment of this two-part podcast continues the conversation with Dr. Giordano on the implications of weaponizing brain science. In an article he wrote for HDIAC in 2016 titled ‘Battlescape Brain’, Dr. Giordano hinted at the possibility of a neuroweapons arms race that could follow from international surveillance. Dr. Giordano provides an updated look at these concerns in the context of today’s environment. He concludes by describing ethical frameworks that could regulate future policies for biotechnology as the world moves forward in this dynamic area.

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Nov 26, 2023

HDIAC Podcast — Weaponizing Brain Science: Neuroweapons — Part 1 of 2

Posted by in categories: chemistry, neuroscience, science, security

https://www.hdiac.org/podcast/neuroweapons-part-1/

In part one of this two-part podcast, HDIAC analyst Mara Kiernan interviews Dr. James Giordano, a Professor in the department of Neurology and Biochemistry at Georgetown University Medical Center. The discussion begins with Dr. Giordano defining neuroweapons and explaining their applied technologies. He provides insight into the manner in which international weapons conventions govern the use neuroweapons and discusses the threats presented by neuroweapons in today’s environment. Dr. Giordano goes on to review the need for continuous monitoring, including his views regarding challenges and potential solutions for effectively understanding global developments in neuroweapon technologies.

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Nov 26, 2023

Examining the biodistribution and function of polymer-DNA origami nanostructures

Posted by in categories: biotech/medical, nanotechnology

The capacity to regulate the biodistribution of therapeutics is a highly desired feature that can limit the side effects of many drugs. In a new study in Scientific Reports, Noah Joseph, and a team of biotechnology and nanoscience scientists in Israel, describe a nanoscale agent developed from a coupled polymer-DNA origami hybrid capable of exhibiting stability in serum and slow diffusion through tissues.

By coupling to fragments of polyethylene glycol through polyamine , the team noted marked stability of the agents in vivo, where more than 90% of the constituents maintained structural integrity for five days after subcutaneous injection.

The findings highlight the polymer-DNA hybrid nanostructures as viable pharmacological agents that can enter mainstream technologies, including their use as monoclonal antibodies for drug activity.

Nov 26, 2023

Two Big Bangs, One Universe: A New Study That Challenges the Standard Cosmological Model

Posted by in categories: cosmology, particle physics

In this video, we will explain a new paper that suggests that there was a second big bang, or a “Dark Big Bang”, that created different kinds of dark matter particles, some of which could be very massive. We will explain how this hypothesis could solve two of the biggest mysteries in cosmology: the origin of the universe and the nature of dark matter. We will also explain how this hypothesis could be tested by future experiments, such as gravitational wave detectors and gamma-ray telescopes. The paper offers a new perspective on the history and structure of the universe, and challenges some of the assumptions and predictions of the standard cosmological model. The paper also opens new possibilities for exploring and understanding the dark sector of the universe, which could reveal new physics and phenomena. So, stay tuned and get ready to explore the dark side of the big bang.

Chapters:
00:00 Introduction.
02:00 The Dark Big Bang.
03:55 The Origin of the Universe.
06:22 The Nature of Dark Matter.
08:27 Outro.
09:03 Enjoy.

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Nov 26, 2023

Researchers discover mechanism for memory storage in engram cells

Posted by in category: neuroscience

What is the mechanism that allows our brains to incorporate new information about the world, and form memories? New work by a team of neuroscientists led by Dr Tomás Ryan from Trinity College Dublin shows that learning occurs through the continuous formation of new connectivity patterns between specific engram cells in different regions of the brain.

Whether on purpose, incidentally, or simply by accident, we are constantly learning and so our brains are constantly changing. When we navigate the world, interact with each other, or consume media content, our brain is grasping information, creating new memories.

The next time we walk down the street, meet our friends, or come across something that reminds us of the last podcast we listened to, we will quickly re-engage that memory information somewhere in our brain. But how do these experiences modify our neurons to allow us to form these new memories?