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Researchers investigate whether dark matter particles actually are produced inside a jet of standard model particles.

The existence of dark matter is a long-standing puzzle in our universe. Dark matter makes up about a quarter of our universe, yet it does not interact significantly with ordinary matter. The existence of dark matter has been confirmed by a series of astrophysical and cosmological observations, including in the stunning recent pictures from the James Webb Space Telescope. However, up to date, no experimental observation of dark matter has been reported. The existence of dark matter has been a question that high energy and astrophysicists around the world have been investigating for decades.

Advancements in Dark Matter Research.

Electrocatalysis expands the ability to generate industrially relevant chemicals locally and on-demand with intermittent renewable energy, thereby improving grid resiliency and reducing supply logistics. Herein, we report the feasibility of using molecular copper boron-imidazolate cages, BIF-29(Cu), to enable coupling between the electroreduction reaction of CO₂ (CO2RR) with NO3– reduction (NO3RR) to produce urea with high selectivity of 68.5% and activity of 424 μA cm–2. Remarkably, BIF-29(Cu) is among the most selective systems for this multistep C–N coupling to-date, despite possessing isolated single-metal sites. The mechanism for C–N bond formation was probed with a combination of electrochemical analysis, in situ spectroscopy, and atomic-scale simulations. We found that NO3RR and CO2RR occur in tandem at separate copper sites with the most favorable C–N coupling pathway following the condensation between *CO and NH2OH to produce urea. This work highlights the utility of supramolecular metal–organic cages with atomically discrete active sites to enable highly efficient coupling reactions.

In our latest feature, we explore the future of gene editing and the challenges we must overcome to harness its full potential.

PSC-brain organoids are typically formed by static medium switches. Here, authors show that a temporal morphogen gradient during neural induction allows the formation of well-specified cortical organoids with a self-organized single neuroepithelium.

Living cells are bombarded with many kinds of incoming molecular signal that influence their behavior. Being able to measure those signals and how cells respond to them through downstream molecular signaling networks could help scientists learn much more about how cells work, including what happens as they age or become diseased.

Right now, this kind of comprehensive study is not possible because current techniques for imaging cells are limited to just a handful of different molecule types within a cell at one time. However, MIT researchers have developed an alternative method that allows them to observe up to seven different molecules at a time, and potentially even more than that.

“There are many examples in biology where an event triggers a long downstream cascade of events, which then causes a specific cellular function,” says Edward Boyden, the Y. Eva Tan Professor in Neurotechnology. “How does that occur? It’s arguably one of the fundamental problems of biology, and so we wondered, could you simply watch it happen?”

Scientists at the University of Bath have used nature as inspiration in developing a new tool that will help researchers develop new pharmaceutical treatments in a cleaner, greener, and less expensive way.

Drug treatments often work by binding to proteins involved in disease and blocking their activity, which either reduces symptoms or treats the disease.

Rather than using conventional small molecules as drugs, which are not well suited to blocking interactions between proteins, the pharmaceutical industry is now investigating the potential of making drugs using small proteins known as ‘peptides,’ which work in a similar way.

The Enabling Technologies Programme (ETP) provides opportunities for the UK space sector to accelerate the development of leading-edge technologies that could be used to tackle global problems and benefit the work of space organisations internationally.

The total government funding is £4 million — made up of £3.2 million from the UK Space Agency with £800,000 contributed by the Science and Technology Facilities Council (STFC), part of UK Research and Innovation (UKRI).

The projects from academia and industry explore how space can be used more efficiently for purposes such as weather prediction, climate-change monitoring, and space debris removal through methods of propulsion, sterilisation, in-orbit servicing, imaging, and more.

As researchers, developers, policymakers and others grapple with navigating socially beneficial advanced technology transitions — especially those associated with artificial intelligence, DNA-based technologies, and quantum technologies — there are valuable lessons to be drawn from nanotechnology. These lessons underscore an urgent need to foster collaboration, engagement and partnerships across disciplines and sectors, together with bringing together people, communities, and organizations with diverse expertise, as they work together to realize the long-term benefits of transformative technologies.

In an extraordinary feat of engineering and international collaboration, the Orion spacecraft, a part of NASA’s Artemis I mission, has achieved a remarkable milestone in space exploration. The spacecraft ventured some 267,000 miles from Earth and roughly 40,000 miles from the Moon, surpassing the distance record set by the Apollo 13 mission over half a century ago.

In this photo, the Orion capsule, along with the Earth and the Moon, appeared to be posing for a ‘family portrait.’ This iconic image marks a pivotal moment in the mission’s journey, symbolizing the culmination of years of meticulous planning and execution.

Orion’s journey from Earth began a year ago, on November 16, 2022, when NASA’s mega Moon rocket, the Space Launch System, lifted off from the Kennedy Space Center in Florida, USA. The uncrewed Orion spacecraft was placed into Earth orbit, marking the beginning of a new era in lunar exploration.