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Undoubtedly one of the most exciting areas within the 3D printing space is that of bioprinting. Using layer-by-layer fabrication methods, a number of companies are in the process of pushing forward a new paradigm shift within the medical implant, transplantation, and surgical spaces. While the media has mainly focused on Organovo, the company behind the world’s first 3D printable liver tissue, there are actually several other companies involved in this incredible space. Here are 3DPrint.com we thought it would be helpful to underline just a handful of those companies that may be about to change medicine as we know it.

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Organovo The company, headquartered in San Diego, California, has been at the forefront of 3D bioprinting research for some time now. Not only are they currently bringing revenues in by providing pharmaceutical companies with their aa3exVive3D™ Liver Tissue for drug toxicity testing, but they have partnered with major companies in the health space including L’Oréal and Merck, and are planning on introducing their exVive3D™ Kidney Tissue product by next year. With an ultimate goal of 3D printing patches made of human tissue for failing organs, and eventually entire organs for transplantation, Organovo certainly has their work cut out for them.

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Scientists have developed a new hydrogel that stretches and contracts just like an artificial muscle. The team created an L-shaped object made out of the hydrogel and immersed it in a water bath. When the water’s temperature was varied, it slowly “walked” forward.

The researchers at the Riken Center for Emergent Matter Science in Japan got the hydrogel to move by tweaking its properties. Polymers like hydrogels carry large amounts of water within their structure which gives them the capacity to respond to variations in environmental factors such as acidity, voltage and temperature. Typically, this response time is quite slow, as the hydrogel must excrete or absorb water to correspondingly shrink or expand.

The Japanese scientists altered the new hydrogel to enable it to contract only in one dimension while expanding in another. Since the hydrogel doesn’t contract equally in every direction, it’s able to alter its shape without absorbing or excreting any water. To test the hydrogel’s properties, the team created an L-shaped polymer and changed the temperature repeatedly to observe its response.

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