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Meanwhile there is something important going on in the fight against baldness.

As in the majority of tissues, the hair follicle has stem cells. There are two types of stem cells that are responsible for the continuous renewal of the follicles. The first type is called active stem cells and they start dividing quite easily. Stem cells of the second type are called quiescent and in case of the new hair growth they don’t start dividing as easily. At the same time, the new hair is based primarily on quiescent cells, which attracted close attention of researchers to these cells. At first people thought that baldness was due to this type of cells.

However, recent studies showed that bald men did have those quiescent cells in their follicles. The problem was that they didn’t divide at all and didn’t contribute to forming new hairs.

This means that even a bald person still has the potential to grow new hair, but because of lack of some regulatory factors quiescent cells can’t start replicating.

Elaine Fuchs was able to identify these regulatory factors in her study published in Cell. Apparently, it’s all about the transit-amplifying cells that are the progeny of the active stem cells.

The U.S. Food and Drug Administration announced on Oct. 27 that it has approved, for the first time, an oncolytic (cancer-killing) viral therapy in the United States. The drug was approved for use against late-stage melanoma, a deadly skin cancer that can be difficult to treat.

The approval came as the result of a recent Phase III study, which showed that more patients with late-stage melanoma, treated with a herpes cold sore virus designed to kill , had a better response when compared to a different treatment. Robert Andtbacka, M.D., from Huntsman Cancer Institute at the University of Utah and Howard L. Kaufman, M.D., from Rutgers Cancer Institute of New Jersey, led the multisite study, published May 26 online in the Journal of Clinical Oncology.

According to Andtbacka, “The goal of this targeted therapy is to treat late stage patients more effectively and with fewer side effects.”

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These people have got a leg — or an arm — up on the future.

Thanks to the latest advancements in medical science, amputees are becoming part robot, with awe-inspiring artificial limbs that would make Luke Skywalker jealous.

These new limbs come armed with microprocessors and electrodes that sense muscle movement. Others can be controlled by a smartphone app. People missing limbs often tried to hide their prosthetics, but these New Yorkers are showing them off with pride.
Rebekah Marine.

Rebekah Marine had the modeling bug from a young age, playing dress-up as a kid and getting her mom to take her to try out for modeling agencies in New York.

The one problem? She was born without part of her right arm.

“I was just kind of quickly denied from [agencies] based on my quote-unquote disability,” the 28-year-old says.

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To many people, the introduction of the first Macintosh computer and its graphical user interface in 1984 is viewed as the dawn of creative computing. But if you ask Dr. Nick Montfort, a poet, computer scientist, and assistant professor of Digital Media at MIT, he’ll offer a different direction and definition for creative computing and its origins.

Defining Creative

Creative Computing was the name of a computer magazine that ran from 1974 through 1985. Even before micro-computing there was already this magazine extolling the capabilities of the computer to teach, to help people learn, help people explore and help them do different types of creative work, in literature, the arts, music and so on,” Montfort said.

“It was a time when people had a lot of hope that computing would enable people personally as artists and creators to do work. It was actually a different time than we’re in now. There are a few people working in those areas, but it’s not as widespread as hoped in the late 70’s or early 80s.”

These days, Montfort notes that many people use the term “artificial intelligence” interchangeably with creative computing. While there are some parallels, Montfort said what is classically called AI isn’t the same as computational creativity. The difference, he says, is in the results.

“A lot of the ways in which AI is understood is the ability to achieve a particular known objective,” Montfort said. “In computational creativity, you’re trying to develop a system that will surprise you. If it does something you already knew about then, by definition, it’s not creative.”

Given that, Montfort quickly pointed out that creative computing can still come from known objectives.

“A lot of good creative computer work comes from doing things we already know computers can do well,” he said. “As a simple example, the difference between a computer as a producer of poetic language and person as a producer of poetic language is, the computer can just do it forever. The computer can just keep reproducing and, (with) that capability to bring it together with images to produce a visual display, now you’re able to do something new. There’s no technical accomplishment, but it’s beautiful nonetheless.”

Models of Creativity

As a poet himself, another area of creative computing that Montfort keeps an eye on is the study of models of creativity used to imitate human creativity. While the goal may be to replicate human creativity, Montfort has a greater appreciation for the end results that don’t necessarily appear human-like.

“Even if you’re using a model of human creativity the way it’s done in computational creativity, you don’t have to try to make something human-like, (even though) some people will try to make human-like poetry,” Montfort said. “I’d much rather have a system that is doing something radically different than human artistic practice and making these bizarre combinations than just seeing the results of imitative work.”

To further illustrate his point, Montfort cited a recent computer generated novel contest that yielded some extraordinary, and unusual, results. Those novels were nothing close to what a human might have written, he said, but depending on the eye of the beholder, it at least bodes well for the future.

“A lot of the future of creative computing is individual engagement with creative types of programs,” Montfort said. “That’s not just using drawing programs or other facilities to do work or using prepackaged apps that might assist creatively in the process of composition or creation, but it’s actually going and having people work to code themselves, which they can do with existing programs, modifying them, learning about code and developing their abilities in very informal ways.”

That future of creative computing lies not in industrial creativity or video games, but rather a sharing of information and revisioning of ideas in the multiple hands and minds of connected programmers, Montfort believes.

“One doesn’t have to get a computer science degree or even take a formal class. I think the perspective of free software and open source is very important to the future of creative programming,” Montfort said. “…If people take an academic project and provide their work as free software, that’s great for all sorts of reasons. It allows people to replicate your results, it allows people to build on your research, but also, people might take the work that you’ve done and inflect it in different types of artistic and creative ways.”