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Human brain is made up of a billion nerve cells called neurons and various other types of cells and is the most complex machine ever known. Even after years of research and studies we still do not have a complete understanding of how it works — how it controls every single thing we ever do. In order to unravel one such mysteries of the brain, researchers at the Carnegie Mellon University set out to find out why brain makes mistakes. The study was conducted as part of Carnegie Mellon’s BrainHub, a university initiative that focuses on how the structure and activity of the brain give rise to complex behaviors.

Brain

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An illustration showing how the “window to the brain” transparent skull implant created by UC Riverside researchers would work (credit: UC Riverside)

Researchers at the University of California, Riverside have developed a transparent “window to the brain” — a skull implant that is biocompatible, infection-resistant, and does not need to be repetitively replaced.

Part of the ongoing “Window to the Brain” project, a multi-institution, cross-disciplinary effort, the idea is to use transparent skull implants to provide laser diagnosis and treatment of a wide variety of brain pathologies, including brain cancers, traumatic brain injury, stroke, and neurodegenerative diseases, without requiring repeated craniotomies (a surgical operation in which a bone flap is temporarily removed from the skull to access the brain). Such operations are vulnerable to bacterial infections.

A biocompatible transparent material

The researchers have developed a transparent version of the material yttria-stabilized zirconia (YSZ), a ceramic material used in hip implants and dental crowns.

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